Impact of Appropriate Use Criteria for Transthoracic Echocardiography in Valvular Heart Disease on Clinical Outcomes.


Journal

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography
ISSN: 1097-6795
Titre abrégé: J Am Soc Echocardiogr
Pays: United States
ID NLM: 8801388

Informations de publication

Date de publication:
12 2020
Historique:
received: 09 05 2020
revised: 17 06 2020
accepted: 26 06 2020
pubmed: 8 9 2020
medline: 25 9 2021
entrez: 7 9 2020
Statut: ppublish

Résumé

The association between appropriate use criteria for transthoracic echocardiography (TTE) and clinical outcomes is unknown for patients with valvular heart disease (VHD). The aim of this study was to identify the association of TTE appropriateness with downstream cardiac tests and clinical outcomes in patients with VHD over 365 days. A subset of 2,297 patients with VHD across six Ontario academic hospitals was selected from the Echo WISELY (Will Inappropriate Scenarios for Echocardiography Lessen Significantly) trial and linked to administrative databases. Each patient's index TTE was classified as "rarely appropriate" (rA) versus "appropriate" (comprising "appropriate" and "may be appropriate" TTE according to the 2011 appropriate use criteria). Overall, 431 of 452 patients with rA TTE were matched 1:1 with patients with appropriate TTE using propensity scores to account for measured confounding. Matched patients with rA TTE were less likely to undergo repeat TTE (relative risk, 0.46; 95% CI, 0.33-0.66) or cardiac catheterization (relative risk, 0.27; 95% CI, 0.16-0.47) at 90 days compared with patients with appropriate TTE. rA TTE was significantly associated with a decreased hazard of aortic valve intervention (hazard ratio, 0.40; 95% CI, 0.14-0.42), all-cause hospitalization (hazard ratio, 0.44; 95% CI, 0.34-0.57), and death (hazard ratio, 0.31; 95% CI, 0.15-0.66) over 365 days of follow-up. Patients with appropriate TTE for VHD were more likely to undergo subsequent cardiac testing within 90 days and valve intervention within 1 year than those with a rA TTE. The 2011 appropriate use criteria for TTE have important clinical implications for outcomes in patient with VHD.

Sections du résumé

BACKGROUND
The association between appropriate use criteria for transthoracic echocardiography (TTE) and clinical outcomes is unknown for patients with valvular heart disease (VHD). The aim of this study was to identify the association of TTE appropriateness with downstream cardiac tests and clinical outcomes in patients with VHD over 365 days.
METHODS
A subset of 2,297 patients with VHD across six Ontario academic hospitals was selected from the Echo WISELY (Will Inappropriate Scenarios for Echocardiography Lessen Significantly) trial and linked to administrative databases. Each patient's index TTE was classified as "rarely appropriate" (rA) versus "appropriate" (comprising "appropriate" and "may be appropriate" TTE according to the 2011 appropriate use criteria). Overall, 431 of 452 patients with rA TTE were matched 1:1 with patients with appropriate TTE using propensity scores to account for measured confounding.
RESULTS
Matched patients with rA TTE were less likely to undergo repeat TTE (relative risk, 0.46; 95% CI, 0.33-0.66) or cardiac catheterization (relative risk, 0.27; 95% CI, 0.16-0.47) at 90 days compared with patients with appropriate TTE. rA TTE was significantly associated with a decreased hazard of aortic valve intervention (hazard ratio, 0.40; 95% CI, 0.14-0.42), all-cause hospitalization (hazard ratio, 0.44; 95% CI, 0.34-0.57), and death (hazard ratio, 0.31; 95% CI, 0.15-0.66) over 365 days of follow-up.
CONCLUSIONS
Patients with appropriate TTE for VHD were more likely to undergo subsequent cardiac testing within 90 days and valve intervention within 1 year than those with a rA TTE. The 2011 appropriate use criteria for TTE have important clinical implications for outcomes in patient with VHD.

Identifiants

pubmed: 32893052
pii: S0894-7317(20)30444-2
doi: 10.1016/j.echo.2020.06.023
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1481-1489

Informations de copyright

Copyright © 2020 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

Auteurs

Jennifer M Amadio (JM)

Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Zachary Bouck (Z)

Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Women's College Hospital, Toronto, Ontario, Canada.

Atul Sivaswamy (A)

ICES, Toronto, Ontario, Canada.

Cherry Chu (C)

Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Women's College Hospital, Toronto, Ontario, Canada.

Peter C Austin (PC)

ICES, Toronto, Ontario, Canada.

David Dudzinski (D)

Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Gillian C Nesbitt (GC)

Cardiology Division, Mount Sinai Hospital, Toronto, Ontario, Canada.

Jeremy Edwards (J)

Division of Cardiology, St. Michael's Hospital, Toronto, Ontario, Canada.

Kibar Yared (K)

The Scarborough Hospital, Toronto, Ontario, Canada.

Brian Wong (B)

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Mark Hansen (M)

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Adina Weinerman (A)

Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

Paaladinesh Thavendiranathan (P)

Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Amer M Johri (AM)

Queen's University, Kingston Health Sciences Centre, Kingston, Ontario, Canada.

Harry Rakowski (H)

Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada.

Michael H Picard (MH)

Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

Rory B Weiner (RB)

Division of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

R Sacha Bhatia (RS)

Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Women's College Hospital, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada. Electronic address: sacha.bhatia@wchospital.ca.

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