[Blepharospasm, dry eye and extractable nuclear antigen antibodies (French translation of the article)].
Blépharospasme, sécheresse oculaire et anticorps anti-nucléaires solubles.
Anticorps anti-SSA
Anticorps anti-SSB
Anticorps nucléaires solubles
Blepharospasm
Blépharospasme
Botulinum NeuroToxin A
Dry eye
Dry eye syndrome
ENA antibodies
Neurotoxine botulique A
Schirmer
Sjögren syndrome
Syndrome de Gougerot-Sjögren
Syndrome oculaire sec
Sécheresse oculaire
anti-SSA antibodies
anti-SSB antibodies
Journal
Journal francais d'ophtalmologie
ISSN: 1773-0597
Titre abrégé: J Fr Ophtalmol
Pays: France
ID NLM: 7804128
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
received:
08
10
2019
revised:
06
11
2019
accepted:
13
11
2019
pubmed:
9
9
2020
medline:
4
11
2020
entrez:
8
9
2020
Statut:
ppublish
Résumé
The goal of this study is to determine a link between benign essential blepharospasm and Sjogren's syndrome by analyzing the presence of extractable nuclear antigens in this population. Seventy-two patients with benign essential blepharospasm (BEB) were included in this study. We eliminated patients with hemifacial spasm or blepharospasm secondary to corneal pathology. We collected the values of the Schirmer I test and the results of the anti-SSA and anti-SSB antibodies. Our study included 72 patients (144 eyes) whose 62 women (86.1%). Mean age was 74.3 years±10.73. Average Schirmer I test was 3.14mm±4.00mm. Five women (8% of this female population) had positive anti-SSA and SSB antibodies. Their mean age was 65.66 years±13.24 whereas the negative antibody patients had an average age of 75.42±9.27. There was no significant difference between their Schimer I test and the Schirmer I of negative antibody population. This study illustrates the possible association between the presence of Sjögren's syndrome and the occurrence of a BEB justifying the search for anti-SSA and anti SSB in blepharospasm patients.
Identifiants
pubmed: 32896450
pii: S0181-5512(20)30304-1
doi: 10.1016/j.jfo.2019.11.038
pii:
doi:
Substances chimiques
Antibodies, Antinuclear
0
Antigens, Nuclear
0
Types de publication
Journal Article
Langues
fre
Sous-ensembles de citation
IM
Pagination
691-696Informations de copyright
Copyright © 2020. Published by Elsevier Masson SAS.