[Blepharospasm, dry eye and extractable nuclear antigen antibodies (French translation of the article)].

Blépharospasme, sécheresse oculaire et anticorps anti-nucléaires solubles.
Anticorps anti-SSA Anticorps anti-SSB Anticorps nucléaires solubles Blepharospasm Blépharospasme Botulinum NeuroToxin A Dry eye Dry eye syndrome ENA antibodies Neurotoxine botulique A Schirmer Sjögren syndrome Syndrome de Gougerot-Sjögren Syndrome oculaire sec Sécheresse oculaire anti-SSA antibodies anti-SSB antibodies

Journal

Journal francais d'ophtalmologie
ISSN: 1773-0597
Titre abrégé: J Fr Ophtalmol
Pays: France
ID NLM: 7804128

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 08 10 2019
revised: 06 11 2019
accepted: 13 11 2019
pubmed: 9 9 2020
medline: 4 11 2020
entrez: 8 9 2020
Statut: ppublish

Résumé

The goal of this study is to determine a link between benign essential blepharospasm and Sjogren's syndrome by analyzing the presence of extractable nuclear antigens in this population. Seventy-two patients with benign essential blepharospasm (BEB) were included in this study. We eliminated patients with hemifacial spasm or blepharospasm secondary to corneal pathology. We collected the values of the Schirmer I test and the results of the anti-SSA and anti-SSB antibodies. Our study included 72 patients (144 eyes) whose 62 women (86.1%). Mean age was 74.3 years±10.73. Average Schirmer I test was 3.14mm±4.00mm. Five women (8% of this female population) had positive anti-SSA and SSB antibodies. Their mean age was 65.66 years±13.24 whereas the negative antibody patients had an average age of 75.42±9.27. There was no significant difference between their Schimer I test and the Schirmer I of negative antibody population. This study illustrates the possible association between the presence of Sjögren's syndrome and the occurrence of a BEB justifying the search for anti-SSA and anti SSB in blepharospasm patients.

Identifiants

pubmed: 32896450
pii: S0181-5512(20)30304-1
doi: 10.1016/j.jfo.2019.11.038
pii:
doi:

Substances chimiques

Antibodies, Antinuclear 0
Antigens, Nuclear 0

Types de publication

Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

691-696

Informations de copyright

Copyright © 2020. Published by Elsevier Masson SAS.

Auteurs

B C Girard (BC)

Service d'ophtalmologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75970 Paris cedex 20, France; UPMC Sorbonne université, Paris, France. Electronic address: docteur.girard@orange.fr.

M Abdellaoui (M)

Service d'ophtalmologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75970 Paris cedex 20, France; UPMC Sorbonne université, Paris, France.

G de Saint Sauveur (G)

Service d'ophtalmologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75970 Paris cedex 20, France; UPMC Sorbonne université, Paris, France.

A Huang (A)

Service d'ophtalmologie, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75970 Paris cedex 20, France; UPMC Sorbonne université, Paris, France.

P Lévy (P)

Département de santé publique, hôpital Tenon, Assistance publique-Hôpitaux de Paris, 4, rue de la Chine, 75970 Paris cedex 20, France; Inserm, Institut Pierre-Louis de Santé Publique, France; UPMC Sorbonne université, Paris, France.

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Classifications MeSH