Acute Pancreatitis in Celiac Disease: Has the Inpatient Prevalence Changed and Is It Associated With Worse Outcomes?
Acute Disease
Adult
Aged
Celiac Disease
/ epidemiology
Comorbidity
Female
Hospital Mortality
Hospitalization
/ statistics & numerical data
Humans
Inpatients
/ statistics & numerical data
Length of Stay
/ statistics & numerical data
Male
Middle Aged
Multivariate Analysis
Outcome Assessment, Health Care
/ methods
Pancreatitis
/ epidemiology
Prevalence
Retrospective Studies
United States
/ epidemiology
Journal
Pancreas
ISSN: 1536-4828
Titre abrégé: Pancreas
Pays: United States
ID NLM: 8608542
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
pubmed:
9
9
2020
medline:
10
8
2021
entrez:
8
9
2020
Statut:
ppublish
Résumé
Studies suggest that adults diagnosed with celiac disease (CD) are at higher risk of developing acute pancreatitis (AP). The aim of this study is to explore the relationship between CD and AP in terms of inpatient prevalence, mortality, morbidity, and resource utilization in the past decade. Retrospective cohort study using the Nationwide Inpatient Sample (2007-2016). The primary outcome was the occurrence of AP in CD patients. Secondary outcomes were the trend in AP cases in CD patients, and mortality, morbidity, length of stay, and total hospital charges and costs. Of 337,201 CD patients identified, 7372 also had AP. The mean age was 53 years, 71% were women. The inpatient prevalence of AP in CD was 2.2% versus 1.2% in non-CD cohort (P < 0.01). Patients with CD displayed increased odds of having AP (adjusted odds ratio, 1.92; P < 0.01). Patients with AP and CD displayed lower odds of morbidity and mortality than non-CD patients with AP. The inpatient prevalence of AP is higher in CD patients, and increased from 2007 to 2016. Patients with CD and AP displayed lower morbidity and mortality, which may suggest that they have a less severe form of AP or lower baseline comorbidity.
Identifiants
pubmed: 32898005
doi: 10.1097/MPA.0000000000001657
pii: 00006676-202010000-00011
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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