The systemic autoinflammatory disorders for dermatologists. Part 1: overview.
Amyloidosis
/ etiology
Cryopyrin-Associated Periodic Syndromes
/ diagnosis
Dermatologists
/ statistics & numerical data
Diagnosis, Differential
Familial Mediterranean Fever
/ diagnosis
Fever
/ diagnosis
Genetic Testing
/ standards
Hereditary Autoinflammatory Diseases
/ diagnosis
Humans
Immune System Diseases
/ complications
Immunity, Innate
/ immunology
Inflammation
/ immunology
Interleukin-1beta
/ immunology
Mevalonate Kinase Deficiency
/ diagnosis
Quality of Life
Severity of Illness Index
Journal
Clinical and experimental dermatology
ISSN: 1365-2230
Titre abrégé: Clin Exp Dermatol
Pays: England
ID NLM: 7606847
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
09
03
2020
accepted:
11
03
2020
pubmed:
10
9
2020
medline:
29
7
2021
entrez:
9
9
2020
Statut:
ppublish
Résumé
The systemic autoinflammatory disorders (SAIDs) or periodic fever syndromes are disorders of innate immunity, which can be inherited or acquired. They are almost all very rare and easily overlooked; typically, patients will have seen multiple specialities prior to diagnosis, so a high level of clinical suspicion is key. It is important to note that these are 'high-value' diagnoses as the majority of these syndromes can be very effectively controlled, dramatically improving quality of life and providing protection against the development of irreversible complications such as AA amyloidosis. In this article, we take an overview of SAIDs and look at the common features; in Part 2, we take a more in-depth look at the better recognized or more dermatologically relevant conditions.
Substances chimiques
Interleukin-1beta
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
962-966Informations de copyright
© 2020 The Authors. Clinical and Experimental Dermatology published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists.
Références
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