Bronchiectasis associated with electronic cigarette use: A case series.

bronchiectasis and primary ciliary dyskinesia environmental lung disease imaging lung pathology pulmonary function testing (PFT)

Journal

Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590

Informations de publication

Date de publication:
12 2020
Historique:
received: 25 05 2020
revised: 19 08 2020
accepted: 02 09 2020
pubmed: 10 9 2020
medline: 26 3 2021
entrez: 9 9 2020
Statut: ppublish

Résumé

Bronchiectasis (BE) is defined as a permanent, irreversible dilation of the bronchial tree. In the pediatric population, this disease process is most commonly associated with patients with cystic fibrosis (CF). However, BE unrelated to CF is increasingly noted as a cause of chronic respiratory related morbidity worldwide. Chronic inflammation and recurrent infection result in cellular cascades that lead to irreversible structural changes of the airways. When these architectural changes occur, they confer extensive risks to morbidity usually due to continued infections. In the adult population, BE has been associated with chronic obstructive pulmonary disease, which is mainly caused by cigarette smoking. In this report, the authors reviewed various cases of BE in the pediatric population at our institution. After a comprehensive case by case review, we compiled details of three cases of newly diagnosed BE where the most likely inciting factor was the electronic cigarette use. Common features of the three cases included at least a year of e-cigarette use with conjunction of tetrahydrocannabinol and radiologic findings of BE, ground glass opacities, and nodule formation.

Identifiants

pubmed: 32902877
doi: 10.1002/ppul.25062
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3443-3449

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

Chang AB, Bush A, Grimwood K. Bronchiectasis in children: diagnosis and treatment. Lancet. 2018;392:866-879.
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Centers for Disease Control and Prevention. Outbreak of lung injury associated with the use of e-cigarette, or vaping, products. 2020. Accessed April 17, 2020.
Kalininskiy A, Bach CT, Nacca NE, et al. E-cigarette, or vaping, product use associated lung injury (EVALI): case series and diagnostic approach. Lancet Respir Med. 2019;7:1017-1026.
Ghosh A, Coakley RD, Ghio AJ, et al. Chronic E-cigarette use increases neutrophil elastase and matrix metalloprotease levels in the lung. Am J Respir Crit Care Med. 2019;200-11:1392-1401.
O'Donnell AE. Bronchiectasis. Chest. 2008;134:815-823.
Amorim A, Bento J, Vaz AP, et al. Bronchiectasis: a retrospective study of clinical and aetiological investigations in general respiratory disease department. Rev Port Pneumol. 2015;21:5-10.
Gao YH, Guan WJ, Liu SX, et al. Aetiology of bronchiectasis in adults: a aystematic literature review. Respiratory. 2016. https://doi.org/10,1111/resp.12832
Martinez CH, Okajima Y, Yen A, et al. Paired CT measures of emphysema and small airway disease and lung function and exercise capacity in smokers with radiologic bronchiectasis. Acad Radiol. 2020:1-9.

Auteurs

Eric S Mull (ES)

Division of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.

Richard Shell (R)

Division of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.
Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.

Brent Adler (B)

Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.
Division of Radiology, Nationwide Children's Hospital, Columbus, Ohio, USA.

Melissa Holtzlander (M)

Division of Pulmonary Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.
Department of Pediatrics, The Ohio State University, Columbus, Ohio, USA.

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