Behavioral and neurological effects of tDCS on speech motor recovery: A single-subject intervention study.
Apraxia of speech
Motor control
Motor learning
Speech
tDCS
Journal
Brain and language
ISSN: 1090-2155
Titre abrégé: Brain Lang
Pays: Netherlands
ID NLM: 7506220
Informations de publication
Date de publication:
11 2020
11 2020
Historique:
received:
01
10
2019
revised:
22
07
2020
accepted:
12
08
2020
pubmed:
10
9
2020
medline:
4
3
2021
entrez:
9
9
2020
Statut:
ppublish
Résumé
This paper reports a feasibility study designed to evaluate the behavioral and neurological effects of using transcranial direct current stimulation (tDCS) in conjunction with speech motor learning treatment for individuals with acquired speech impairment subsequent to stroke. Most of the research using tDCS to enhance treatment outcomes in stroke recovery has focused on either limb motor control or aphasia treatment. Using a multiple-baseline multiple-probe crossover design, we compared both behavioral and brain connectivity-based outcomes following speech motor learning treatment with both Active tDCS and Sham tDCS. We observed that both treatment phases led to improvement in short-term maintenance, but that Active tDCS was associated with greater long-term maintenance improvement. Active tDCS was also associated with an increase in functional connectivity in the left hemisphere and interhemispherically in an ROI-based network analysis examining correlations among areas associated with speech production and acquired speech impairment. This report supports the possibility that tDCS may enhance both behavioral and neurological outcomes and indicates the importance of additional work in this area, although replication is required to confirm the extent and consistency of tDCS benefits on speech motor learning treatment outcomes.
Identifiants
pubmed: 32905863
pii: S0093-934X(20)30108-5
doi: 10.1016/j.bandl.2020.104849
pmc: PMC7554139
mid: NIHMS1628556
pii:
doi:
Types de publication
Clinical Study
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104849Subventions
Organisme : NIDCD NIH HHS
ID : K01 DC014298
Pays : United States
Organisme : NIDCD NIH HHS
ID : R01 DC018589
Pays : United States
Informations de copyright
Copyright © 2020 Elsevier Inc. All rights reserved.
Références
Neuroimage Clin. 2017 Oct 28;17:297-305
pubmed: 29527477
Brain Stimul. 2017 Jan - Feb;10(1):51-58
pubmed: 28104085
Brain Stimul. 2012 Oct;5(4):499-504
pubmed: 22405745
Neuropsychol Rev. 2006 Dec;16(4):161-9
pubmed: 17151940
Comput Biomed Res. 1996 Jun;29(3):162-73
pubmed: 8812068
Am J Speech Lang Pathol. 2008 Aug;17(3):277-98
pubmed: 18663111
Neuroimage. 2004;23 Suppl 1:S208-19
pubmed: 15501092
JAMA Neurol. 2018 Dec 1;75(12):1470-1476
pubmed: 30128538
Brain. 2005 Mar;128(Pt 3):490-9
pubmed: 15634731
Cereb Cortex. 2016 Aug;26(8):3508-26
pubmed: 27230218
Brain Stimul. 2018 Jul - Aug;11(4):727-733
pubmed: 29576498
Am J Speech Lang Pathol. 2015 May 1;24(2):316-337
pubmed: 25815778
J Speech Lang Hear Res. 2015 Oct;58(5):1464-81
pubmed: 26184118
Front Hum Neurosci. 2017 Feb 28;11:91
pubmed: 28293185
J Speech Lang Hear Res. 2012 Oct;55(5):S1573-86
pubmed: 23033450
Neuroimage. 2020 May 1;211:116598
pubmed: 32032738
Brain Stimul. 2011 Jul;4(3):169-74
pubmed: 21777878
Neuroimage. 2013 Oct 15;80:263-72
pubmed: 23571422
J Speech Lang Hear Res. 2017 Jun 22;60(6S):1726-1738
pubmed: 28655044
Cortex. 2019 Feb;111:274-285
pubmed: 30551048
Am J Phys Med Rehabil. 2010 Nov;89(11):879-86
pubmed: 20962598
Brain. 2001 Jun;124(Pt 6):1171-81
pubmed: 11353733
J Cogn Neurosci. 2016 May;28(5):724-38
pubmed: 26807842
Psychol Sci. 2011 Sep;22(9):1113-9
pubmed: 21828349
Med Image Anal. 2008 Feb;12(1):26-41
pubmed: 17659998
Neuroimage Clin. 2015 Mar 25;8:429-39
pubmed: 26106568
Front Hum Neurosci. 2013 Oct 21;7:688
pubmed: 24155708
Behav Neurol. 2000;12(4):191-200
pubmed: 11568431
Stroke. 2017 Jan;48(1):229-232
pubmed: 27899754
Neuroscience. 2019 May 15;406:159-166
pubmed: 30876982
Arch Ital Biol. 2010 Sep;148(3):219-41
pubmed: 21175010