Cryptic transmission of SARS-CoV-2 in Washington state.


Journal

Science (New York, N.Y.)
ISSN: 1095-9203
Titre abrégé: Science
Pays: United States
ID NLM: 0404511

Informations de publication

Date de publication:
30 10 2020
Historique:
received: 03 04 2020
accepted: 08 09 2020
pubmed: 12 9 2020
medline: 18 11 2020
entrez: 11 9 2020
Statut: ppublish

Résumé

After its emergence in Wuhan, China, in late November or early December 2019, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly spread globally. Genome sequencing of SARS-CoV-2 allows the reconstruction of its transmission history, although this is contingent on sampling. We analyzed 453 SARS-CoV-2 genomes collected between 20 February and 15 March 2020 from infected patients in Washington state in the United States. We find that most SARS-CoV-2 infections sampled during this time derive from a single introduction in late January or early February 2020, which subsequently spread locally before active community surveillance was implemented.

Identifiants

pubmed: 32913002
pii: science.abc0523
doi: 10.1126/science.abc0523
pmc: PMC7810035
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

571-575

Subventions

Organisme : NIAID NIH HHS
ID : R21 AI129455
Pays : United States
Organisme : NHGRI NIH HHS
ID : RM1 HG010461
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM119774
Pays : United States
Organisme : NCI NIH HHS
ID : K08 CA230156
Pays : United States
Organisme : Wellcome Trust
Pays : United Kingdom

Investigateurs

Helen Y Chu (HY)
Michael Boeckh (M)
Janet A Englund (JA)
Michael Famulare (M)
Barry R Lutz (BR)
Deborah A Nickerson (DA)
Mark J Rieder (MJ)
Lea M Starita (LM)
Matthew Thompson (M)
Jay Shendure (J)
Trevor Bedford (T)
Amanda Adler (A)
Elisabeth Brandstetter (E)
Shari Cho (S)
Chris D Frazar (CD)
Danielle Giroux (D)
Peter D Han (PD)
James Hadfield (J)
Shichu Huang (S)
Michael L Jackson (ML)
Anahita Kiavand (A)
Louise E Kimball (LE)
Kirsten Lacombe (K)
Jennifer Logue (J)
Victoria Lyon (V)
Kira L Newman (KL)
Matthew Richardson (M)
Thomas R Sibley (TR)
Monica L Zigman Suchsland (ML)
Melissa Truong (M)
Caitlin R Wolf (CR)

Commentaires et corrections

Type : UpdateOf

Informations de copyright

Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.

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Auteurs

Trevor Bedford (T)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA. tbedford@fredhutch.org.
Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Alexander L Greninger (AL)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Pavitra Roychoudhury (P)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Lea M Starita (LM)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Michael Famulare (M)

Institute for Disease Modeling, Bellevue, WA, USA.

Meei-Li Huang (ML)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Arun Nalla (A)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Gregory Pepper (G)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Adam Reinhardt (A)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Hong Xie (H)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Lasata Shrestha (L)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Truong N Nguyen (TN)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Amanda Adler (A)

Division of Infectious Disease, Seattle Children's Hospital, Seattle, WA, USA.

Elisabeth Brandstetter (E)

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.

Shari Cho (S)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Danielle Giroux (D)

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Peter D Han (PD)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Kairsten Fay (K)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Chris D Frazar (CD)

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Misja Ilcisin (M)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Kirsten Lacombe (K)

Division of Infectious Disease, Seattle Children's Hospital, Seattle, WA, USA.

Jover Lee (J)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Anahita Kiavand (A)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Matthew Richardson (M)

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Thomas R Sibley (TR)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Melissa Truong (M)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Caitlin R Wolf (CR)

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.

Deborah A Nickerson (DA)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Mark J Rieder (MJ)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.

Janet A Englund (JA)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Division of Infectious Disease, Seattle Children's Hospital, Seattle, WA, USA.
Department of Pediatrics, University of Washington, Seattle, WA, USA.

James Hadfield (J)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Emma B Hodcroft (EB)

Biozentrum, University of Basel, Basel, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

John Huddleston (J)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Molecular and Cellular Biology Program, University of Washington, Seattle, WA, USA.

Louise H Moncla (LH)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Nicola F Müller (NF)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Richard A Neher (RA)

Biozentrum, University of Basel, Basel, Switzerland.
Swiss Institute of Bioinformatics, Lausanne, Switzerland.

Xianding Deng (X)

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.

Wei Gu (W)

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.

Scot Federman (S)

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.

Charles Chiu (C)

Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA, USA.

Jeffrey S Duchin (JS)

Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.
Public Health - Seattle & King County, Seattle, WA, USA.

Romesh Gautom (R)

Washington State Department of Health, Shoreline, WA, USA.

Geoff Melly (G)

Washington State Department of Health, Shoreline, WA, USA.

Brian Hiatt (B)

Washington State Department of Health, Shoreline, WA, USA.

Philip Dykema (P)

Washington State Department of Health, Shoreline, WA, USA.

Scott Lindquist (S)

Washington State Department of Health, Shoreline, WA, USA.

Krista Queen (K)

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Ying Tao (Y)

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Anna Uehara (A)

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Suxiang Tong (S)

Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Duncan MacCannell (D)

Office of Advanced Molecular Detection, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Gregory L Armstrong (GL)

Office of Advanced Molecular Detection, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Geoffrey S Baird (GS)

Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

Helen Y Chu (HY)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.

Jay Shendure (J)

Brotman Baty Institute for Precision Medicine, Seattle, WA, USA.
Department of Genome Sciences, University of Washington, Seattle, WA, USA.
Howard Hughes Medical Institute, Seattle, WA, USA.

Keith R Jerome (KR)

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, USA.

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Classifications MeSH