Performance of diagnostic ultrasound to identify causes of hydramnios.


Journal

Prenatal diagnosis
ISSN: 1097-0223
Titre abrégé: Prenat Diagn
Pays: England
ID NLM: 8106540

Informations de publication

Date de publication:
01 2021
Historique:
received: 18 06 2020
revised: 01 09 2020
accepted: 01 09 2020
pubmed: 14 9 2020
medline: 20 11 2021
entrez: 13 9 2020
Statut: ppublish

Résumé

We aimed to assess the diagnostic yield of ultrasonography in the identification of the etiology of hydramnios, and the added value of MRI or amniocentesis. We conducted a single-center retrospective study including pregnancies with confirmed hydramnios (defined as deepest pocket ≥8 cm) between January 2013 and May 2017. Twin pregnancies, secondary hydramnios discovered after the diagnosis of a causal pathology, and pregnancies of unknown outcome were excluded. All pregnancies underwent a targeted scan, and selected cases underwent MRI or amniocentesis. A total of 158 patients with confirmed hydramnios were included. Hydramnios was associated with a fetal pathology in 37 cases (23.4%), with diabetes in 39 (24.6%), isolated macrosomia in 16 (10.1%), and considered idiopathic in 66 (41.7%). Ultrasonography established a diagnosis of the underlying pathology in 73% of cases. Amniocentesis was done in 31 cases (20%) and it allowed diagnosis of chromosome anomalies, esophageal atresia, myotonic dystrophy congenital type, Prader-Willi syndrome, and Bartter syndrome. MRI was done in 15 cases (10%) and it allowed one additional diagnosis of esophageal atresia. The diagnostic yields of MRI and amniocentesis were 91.7% and 95.2%, respectively. There were five false positive diagnoses at ultrasonography, and one false positive diagnosis at MRI. Hydramnios can be associated with a wide variety of underlying pathologies. Diagnostic ultrasound can attain a diagnosis in the majority of cases. Amniocentesis offers a valuable complementary assessment.

Identifiants

pubmed: 32920845
doi: 10.1002/pd.5825
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

111-122

Informations de copyright

© 2020 John Wiley & Sons Ltd.

Références

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Auteurs

Marie-José Adam (MJ)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.

Isabelle Enderle (I)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.
CIC Inserm 1414, University Hospital of Rennes, University of Rennes, Rennes, France.

Gwenaëlle Le Bouar (G)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.

Anne-Sophie Cabaret-Dufour (AS)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.

Cécile Tardif (C)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.

Laurence Contin (L)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.

Alexis Arnaud (A)

Department of Pediatric Surgery, University Hospital of Rennes, Rennes, France.

Maïa Proisy (M)

Department of Radiology, University Hospital of Rennes, Rennes, France.

Sylvie Jaillard (S)

Department of Cytogenetics, University Hospital of Rennes, Rennes, France.

Laurent Pasquier (L)

Department of Genetics, University Hospital of Rennes, Rennes, France.

Maela Le Lous (M)

Department of Obstetrics and Gynecology, University Hospital of Rennes, Rennes, France.
CIC Inserm 1414, University Hospital of Rennes, University of Rennes, Rennes, France.

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