Outcomes of secondary intraocular lens implantation in the Infant Aphakia Treatment Study.
Journal
Journal of cataract and refractive surgery
ISSN: 1873-4502
Titre abrégé: J Cataract Refract Surg
Pays: United States
ID NLM: 8604171
Informations de publication
Date de publication:
01 02 2021
01 02 2021
Historique:
received:
12
05
2020
accepted:
16
08
2020
pubmed:
15
9
2020
medline:
29
7
2021
entrez:
14
9
2020
Statut:
ppublish
Résumé
To report outcomes of secondary intraocular lens (IOL) implantation in the Infant Aphakia Treatment Study (IATS). Multicenter clinical practice. Secondary analysis of patients enrolled in a randomized clinical trial. Details regarding all secondary IOL surgeries conducted in children enrolled in the IATS were compiled. Visual outcomes, refractive outcomes, and adverse events at the age of 10½ years were evaluated. Comparisons were made with eyes that remained aphakic and with eyes randomized to primary IOL placement. The study included 114 infants, 57 in the aphakic group and 57 in the primary IOL group; 55 of 57 patients randomized to aphakia with contact lens correction were seen for the 10½-year study visit; 24 (44%) of 55 eyes had secondary IOL surgery. Median age at IOL surgery was 5.4 years (range 1.7 to 10.3 years). Mean absolute prediction error was 1.00 ± 0.70 diopters (D). At age 10½ years, the median logarithm of the minimum angle of resolution visual acuity (VA) was 0.9 (range 0.2 to 1.7), similar to VA in the 31 eyes still aphakic (0.8, range 0.1 to 2.9); the number of eyes with stable or improved VA scores between the 4½-year and 10½-year study visits was also similar (78% secondary IOL eyes; 84% aphakic eyes). For eyes undergoing IOL implantation after the 4½-year study visit (n = 22), the mean refraction at age 10½ years was -3.20 ± 2.70 D (range -9.90 to 1.10 D), compared with -5.50 ± 6.60 D (n = 53, range -26.50 to 3.00 D) in eyes with primary IOL (P = .03). Delayed IOL implantation allows a more predictable refractive outcome at age 10½ years, although the range of refractive error is still large.
Identifiants
pubmed: 32925650
pii: 02158034-202102000-00006
doi: 10.1097/j.jcrs.0000000000000412
pmc: PMC7936988
mid: NIHMS1625865
doi:
Banques de données
ClinicalTrials.gov
['NCT00212134']
Types de publication
Journal Article
Multicenter Study
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
172-177Subventions
Organisme : NEI NIH HHS
ID : UG1 EY013287
Pays : United States
Organisme : NEI NIH HHS
ID : P30 EY026877
Pays : United States
Organisme : NEI NIH HHS
ID : U10 EY013272
Pays : United States
Organisme : NEI NIH HHS
ID : U10 EY013287
Pays : United States
Organisme : NEI NIH HHS
ID : UG1 EY025553
Pays : United States
Organisme : NEI NIH HHS
ID : UG1 EY013272
Pays : United States
Informations de copyright
Copyright © 2021 Published by Wolters Kluwer on behalf of ASCRS and ESCRS.
Références
Birch EE, Stager DR. Prevalence of good visual acuity following surgery for congenital unilateral cataract. Arch Ophthalmol 1988;106:40–43
Chan WH, Biswas S, Ashworth JL, Lloyd IC. Congenital and infantile cataract: aetiology and management. Eur J Pediatr 2012;171:625–630
Allen RJ, Speedwell L, Russell-Eggitt I. Long-term visual outcome after extraction of unilateral congenital cataracts. Eye (Lond) 2010;24:1263–1267
Lambert SL. Management of monocular congenital cataracts. Eye (Lond) 1999;13(pt 3b):474–479
Infant Aphakia Treatment Study Group, Lambert SR, Buckley EG, Drews-Botsch C, DuBois L, Hartmann E, Lynn MJ, Plager DA, Wilson ME. The infant aphakia treatment study: design and clinical measures at enrollment. Arch Ophthalmol 2010;128:21–27
Infant Aphakia Treatment Study Group, Lambert SR, Buckley EG, Drews-Botsch C, DuBois L, Hartmann EE, Lynn MJ, Plager DA, Wilson ME. A randomized clinical trial comparing contact lens with intraocular lens correction of monocular aphakia during infancy: grating acuity and adverse events at age 1 year. Arch Ophthalmol 2010;128:810–818
Infant Aphakia Treatment Study Group, Lambert SR, Lynn MJ, Hartmann EE, DuBois L, Drews-Botsch C, Freedman SF, Plager DA, Buckley EG, Wilson ME. Comparison of contact lens and intraocular lens correction of monocular aphakia during infancy: a randomized clinical trial of HOTV optotype acuity at age 4.5 years and clinical findings at age 5 years. JAMA Ophthalmol 2014;132:676–682
Lambert SR, Cotsonis G, DuBois L, Nizam A, Kruger SJ, Hartmann EE, Weakley DR Jr, Drews-Botsch C; Infant Aphakia Treatment Study Group. Long-term effect of intraocular lens vs contact lens correction on visual acuity after cataract surgery during infancy: a randomized clinical trial. JAMA Ophthalmol 2020;138:365–372
Wilson ME Jr, Englert JA, Greenwald MJ. In-the-bag secondary intraocular lens implantation in children. J AAPOS 1999;3:350–355
Nihalani BR, Vanderveen DK. Secondary intraocular lens implantation after pediatric aphakia. J AAPOS 2011;15:435–440
Grewal DS, Basti S. Modified technique for removal of Soemmerring ring and in-the-bag secondary intraocular lens placement in aphakic eyes. J Cataract Refract Surg 2012;38:739–742
Shenoy BH, Mittal V, Gupta A, Sachdeva V, Kekunnaya R. Complications and visual outcomes after secondary intraocular lens implantation in children. Am J Ophthalmol 2015;159:720–726
Crnic T, Weakley DR Jr, Stager D Jr, Felius J. Use of Acrysof acrylic foldable intraocular lens for secondary implantation in children. J AAPOS 2004;8:151–155
Trivedi RH, Wilson ME Jr, Facciani J. Secondary intraocular lens implantation for pediatric aphakia. J AAPOS 2005;9:346–352
Wood KS, Tadros D, Trivedi RH, Wilson ME. Secondary intraocular lens implantation following infantile cataract surgery: intraoperative indications, postoperative outcomes. Eye (Lond) 2016;30:1182–1186
Nihalani BR, VanderVeen DK. Benchmarks for outcome indicators in pediatric cataract surgery. Eye (Lond) 2017;31:417–421
VanderVeen DK, Nizam A, Lynn MJ, Bothun ED, McClatchey SK, Weakley DR, DuBois LG, Lambert SR; Infant Aphakia Treatment Study Group. Predictability of intraocular lens calculation and early refractive status: the Infant Aphakia Treatment Study. Arch Ophthalmol 2012;130:293–299
Vanderveen DK, Trivedi RH, Nizam A, Lynn MJ, Lambert SR; Infant Aphakia Treatment Study Group. Predictability of intraocular lens power calculation formulae in infantile eyes with unilateral congenital cataract: results from the Infant Aphakia Treatment Study. Am J Ophthalmol 2013;156:1252–1260
Moore DB, Ben Zion I, Neely DE, Roberts GJ, Sprunger DT, Plager DA. Refractive outcomes with secondary intraocular lens implantation in children. J AAPOS 2009;13:551–554
Nihalani BR, Vanderveen DK. Secondary intraocular lens implantation after pediatric aphakia. J AAPOS 2011;15:435–440
Shenoy BH, Mittal V, Gupta A, Sachdeva V, Kekunnaya R. Refractive outcomes and prediction error following secondary intraocular lens implantation in children: a decade-long analysis. Br J Ophthalmol 2013;97:1516–1519
IOL Power Calculations: Bag vs. Sulcus IOL Power. Available at: https://www.doctor-hill.com/iol-main/bag-sulcus.htm . Accessed September 18, 2020
Plager DA, Lynn MJ, Buckley EG, Wilson ME, Lambert SR; Infant Aphakia Treatment Study Group. Complications in the first 5 years following cataract surgery in infants with and without intraocular lens implantation in the Infant Aphakia Treatment Study. Am J Ophthalmol 2014;158:892–898
Beck AD, Freedman SF, Lynn MJ, Bothun E, Neely DE, Lambert SR; Infant Aphakia Treatment Study Group. Glaucoma-related adverse events in the Infant Aphakia Treatment Study: 1-year results. Arch Ophthalmol 2012;130:300–305
Wilson ME, Trivedi RH, Weakley DR Jr, Cotsonis GA, Lambert SR; Infant Aphakia Treatment Study Group. Globe axial length growth at age 5 years in the Infant Aphakia Treatment Study. Ophthalmology 2017;124:730–733
Wilson ME, Trivedi RH, Weakley DR Jr, Cotsonis GA, Lambert SR, for the Infant Aphakia Treatment Study. Globe axial length growth at age 10.5 years in the Infant Aphakia Treatment Study. Am J Ophthalmol 2020;216:147–155
Weakley DR Jr, Lynn MJ, Dubois L, Cotsonis G, Wilson ME, Buckley EG, Plager DA, Lambert SR; Infant Aphakia Treatment Study Group. Myopic shift 5 years after intraocular lens implantation in the Infant Aphakia Treatment Study Ophthalmology 2017;124:822–827
Bothun ED, Lynn MJ, Christiansen SP, Neely DE, Vanderveen DK, Kruger SJ, Lambert SR; Infant Aphakia Treatment Study Group. Sensorimotor outcomes by age 5 years after monocular cataract surgery in the Infant Aphakia Treatment Study (IATS). J AAPOS 2016;20:49–53