Atrial fibrillation in horses part 1: Pathophysiology.


Journal

Veterinary journal (London, England : 1997)
ISSN: 1532-2971
Titre abrégé: Vet J
Pays: England
ID NLM: 9706281

Informations de publication

Date de publication:
Sep 2020
Historique:
received: 08 01 2020
revised: 05 07 2020
accepted: 21 07 2020
entrez: 15 9 2020
pubmed: 16 9 2020
medline: 16 1 2021
Statut: ppublish

Résumé

Atrial fibrillation (AF) is the most common clinically relevant arrhythmia in horses, with a reported prevalence up to 2.5%. The pathophysiology has mainly been investigated in experimental animal models and human medicine, with limited studies in horses. Atrial fibrillation results from the interplay between electrical triggers and a susceptible substrate. Triggers consist of atrial premature depolarizations due to altered automaticity or triggered activity, or local (micro)reentry. The arrhythmia is promoted by atrial myocardial ion channel alterations, Ca

Identifiants

pubmed: 32928494
pii: S1090-0233(20)30098-8
doi: 10.1016/j.tvjl.2020.105521
pii:
doi:

Substances chimiques

Ion Channels 0
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105521

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Annelies Decloedt (A)

Equine Cardioteam Gent University, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Belgium. Electronic address: annelies.decloedt@ugent.be.

Glenn Van Steenkiste (G)

Equine Cardioteam Gent University, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Belgium.

Lisse Vera (L)

Equine Cardioteam Gent University, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Belgium.

Rikke Buhl (R)

Department of Veterinary Clinical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

Gunther van Loon (G)

Equine Cardioteam Gent University, Department of Large Animal Internal Medicine, Faculty of Veterinary Medicine, Ghent University, Belgium.

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Classifications MeSH