Towards MR-guided electron therapy: Measurement and simulation of clinical electron beams in magnetic fields.

Electrons Magnetic Fields Magnetic Resonance Imaging Monte Carlo Method Particle Accelerators
Electron therapy MRI-linac Magnetic fields Monte Carlo

Journal

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
ISSN: 1724-191X
Titre abrégé: Phys Med
Pays: Italy
ID NLM: 9302888

Informations de publication

Date de publication:
Oct 2020
Historique:
received: 10 02 2020
revised: 17 08 2020
accepted: 01 09 2020
pubmed: 20 9 2020
medline: 25 6 2021
entrez: 19 9 2020
Statut: ppublish

Résumé

In the current era of MRI-linac radiotherapy, dose optimization with arbitrary dose distributions is a reality. For the first time, we present new and targeted experiments and modeling to aid in evaluating the potential dose improvements offered with an electron beam mode during MRI-linac radiotherapy. Small collimated (1 cm diameter and 1.5 × 1.5 cm With perpendicular fields a 5% narrowing of the beam FWHM and a 10 mm reduction in the 15% isodose penetration is seen for the 20 MeV beam. In the inline setup the penumbral width is reduced by up to 20%, and a local central dose enhancement of 100% is observed. Monte Carlo simulations are in agreement with the measured dose distributions (2% or 2 mm). A new range of experiments have been performed to offer insight into how an electron beam mode could offer additional choices in MRI-linac radiotherapy. The work extends on historic studies to bring a successful unified experimental and Monte Carlo modeling approach for studying small field electron beam dosimetry inside magnetic fields. The results suggest further work, particularly on the inline magnetic field scenario.

Identifiants

DOI: 10.1016/j.ejmp.2020.09.001 PMID: 32950017
pubmed: 32950017
pii: S1120-1797(20)30216-7
doi: 10.1016/j.ejmp.2020.09.001
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

83-92

Informations de copyright

Copyright © 2020 Associazione Italiana di Fisica Medica. Published by Elsevier Ltd. All rights reserved.

Auteurs

R Kueng (R)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland. Electronic address: reto.kueng@insel.ch.

B M Oborn (BM)

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia; Illawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia.

N F Roberts (NF)

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia.

T Causer (T)

Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW, Australia; Illawarra Cancer Care Centre, Wollongong Hospital, Wollongong, NSW, Australia.

M F M Stampanoni (MFM)

Institute for Biomedical Engineering, University of Zurich and Swiss Federal Institute of Technology (ETH), Zurich, Switzerland.

P Manser (P)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.

P J Keall (PJ)

ACRF Image X Institute, Sydney Medical School, University of Sydney, Australia.

M K Fix (MK)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland.

Articles similaires

Pulmonary Atelectasis After Sedation With Propofol vs Propofol-Ketamine for Magnetic Resonance Imaging in Children: A Randomized Clinical Trial.

Yu Jeong Bang, Jeayoun Kim, Nam-Su Gil et al.
1.00
Humans Ketamine Propofol Pulmonary Atelectasis Female

Customization of neonatal functional magnetic resonance imaging: A preclinical phantom-based study.

Juan F Quinones, Tina Schmitt, Tommaso Pavan et al.
1.00
Humans Magnetic Resonance Imaging Phantoms, Imaging Infant, Newborn Signal-To-Noise Ratio

Multilabel SegSRGAN-A framework for parcellation and morphometry of preterm brain in MRI.

Guillaume Dollé, Gauthier Loron, Margaux Alloux et al.
1.00
Humans Magnetic Resonance Imaging Brain Infant, Newborn Infant, Premature

Defining multilevel developmental cervical spinal stenosis using MRI.

Prudence W H Cheung, Justin H M Leung, Vivien W Y Lee et al.
1.00
Humans Male Female Magnetic Resonance Imaging Middle Aged

Classifications MeSH

questionsmedicales.fr › Phénomènes physiques › Phénomènes magnétiques › Phénomènes électromagnétiques › Électrons › Towards MR-guided electron therapy:...
questionsmedicales.fr › Phénomènes physiques › Phénomènes magnétiques › Champs magnétiques › Towards MR-guided electron therapy:...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Towards MR-guided electron therapy:...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Méthode de Monte Carlo › Towards MR-guided electron therapy:...
questionsmedicales.fr › Équipement et fournitures › Équipement et fournitures pour les applications des radiations › Accélérateurs de particules › Towards MR-guided electron therapy:...