Quantitative analysis of enteric neurons containing choline acetyltransferase and nitric oxide synthase immunoreactivities in the submucosal and myenteric plexuses of the porcine colon.
Enteric nervous system
Excitatory motor neurons
Inhibitory motor neurons
Interneurons
Secretomotor neurons
Journal
Cell and tissue research
ISSN: 1432-0878
Titre abrégé: Cell Tissue Res
Pays: Germany
ID NLM: 0417625
Informations de publication
Date de publication:
Feb 2021
Feb 2021
Historique:
received:
23
03
2020
accepted:
17
08
2020
pubmed:
24
9
2020
medline:
23
9
2021
entrez:
23
9
2020
Statut:
ppublish
Résumé
The enteric nervous system (ENS) controls gastrointestinal functions. In large mammals' intestine, it comprises an inner (ISP) and outer (OSP) submucous plexus and a myenteric plexus (MP). This study quantifies enteric neurons in the ISP, OSP, and MP of the pig ascending (AC) and descending colon (DC) using the HuC/D, choline acetyltransferase (ChAT), and neuronal nitric oxide synthase (nNOS) neuronal markers in whole mount preparations with multiple labeling immunofluorescence. We established that the ISP contains the highest number of HuC/D neurons/mm
Identifiants
pubmed: 32965550
doi: 10.1007/s00441-020-03286-7
pii: 10.1007/s00441-020-03286-7
pmc: PMC8059758
mid: NIHMS1631870
doi:
Substances chimiques
Nitric Oxide Synthase
EC 1.14.13.39
Choline O-Acetyltransferase
EC 2.3.1.6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
645-654Subventions
Organisme : National Institute of Health
ID : 1OT2OD24899
Organisme : NIDDK NIH HHS
ID : P30 DK41301 Animal Core
Pays : United States
Organisme : National Institutes of Health (US)
ID : 1OT2OD24899
Organisme : CARISBO
ID : project 2017/0312
Organisme : NIDDK NIH HHS
ID : P30 DK041301
Pays : United States
Organisme : NIH HHS
ID : OT2 OD024899
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK41301 Imaging Core
Pays : United States
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