Highly Sensitive Bacteria-Responsive Membranes Consisting of Core-Shell Polyurethane Polyvinylpyrrolidone Electrospun Nanofibers for In Situ Detection of Bacterial Infections.
chromogenic probe
color changing properties
nanofibrous membrane
point of care diagnosis
wound infection
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
14 Oct 2020
14 Oct 2020
Historique:
pubmed:
25
9
2020
medline:
11
3
2021
entrez:
24
9
2020
Statut:
ppublish
Résumé
Bacteria responsive color-changing wound dressings offer a valuable platform for continuous monitoring of the wound bed facilitating early detection of bacterial infections. In this study, we present a highly sensitive electrospun nanofibrous polyurethane wound dressing incorporating a hemicyanine-based chromogenic probe with a labile ester linkage that can be enzymatically cleaved by bacterial lipase released from clinically relevant strains, such as
Identifiants
pubmed: 32967419
doi: 10.1021/acsami.0c14213
doi:
Substances chimiques
Polyurethanes
0
Lipase
EC 3.1.1.3
Povidone
FZ989GH94E
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM