First report of
DNA sequencing
Mortierella wolfii
fungal keratitis
non sporulating mould (NSM)
therapeutic penetrating keratoplasty
Journal
Indian journal of ophthalmology
ISSN: 1998-3689
Titre abrégé: Indian J Ophthalmol
Pays: India
ID NLM: 0405376
Informations de publication
Date de publication:
Oct 2020
Oct 2020
Historique:
entrez:
25
9
2020
pubmed:
26
9
2020
medline:
15
5
2021
Statut:
ppublish
Résumé
A young 33 year old male presented with non-resolving corneal infiltrate for 2 month duration in the right eye. KOH/ Calcoflour wet mount revealed sparsely septate fungal hyphae. Post therapeutic penetrating keratoplasty 3 doses of intracameral voriconazole(100μg/0.1ml) was administered suspecting recurrence. Fungal culture revealed non sporulating mould on SDA. PCR based DNA sequencing targeting the ITS region identified the fungal isolate as Mortierella wolfii (M. wolfii) belonging to zygomycetes. To the best of our knowledge, this is the first report of human fungal keratitis caused by M. wolfii.
Identifiants
pubmed: 32971689
pii: IndianJOphthalmol_2020_68_10_2272_295699
doi: 10.4103/ijo.IJO_2136_19
pmc: PMC7727982
doi:
Substances chimiques
Antifungal Agents
0
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
2272-2274Déclaration de conflit d'intérêts
None
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