Suicidality Over the First 5 Years of Psychosis: Does Extending Early Intervention Have Benefits?
RCT
depressive symptoms
early intervention
first-episode psychosis
longitudinal course
suicidality
Journal
Canadian journal of psychiatry. Revue canadienne de psychiatrie
ISSN: 1497-0015
Titre abrégé: Can J Psychiatry
Pays: United States
ID NLM: 7904187
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
pubmed:
29
9
2020
medline:
21
10
2021
entrez:
28
9
2020
Statut:
ppublish
Résumé
We aimed to investigate whether individuals with first-episode psychosis (FEP) receiving extended early intervention (EI) were less likely to experience suicidal ideation and behaviors than those transferred to regular care after 2 years of EI. Another objective was to examine the 5-year course of suicidality in FEP. We conducted a secondary analysis of a randomized controlled trial where 220 patients were randomized after 2 years of EI to receive extended EI or regular care for the subsequent 3 years. Suicidality was rated using the Brief Psychiatric Rating Scale. Linear mixed model analysis was used to study time and group effects on suicidality. Extended EI and regular care groups did not differ on suicidality. There was a small decrease in suicidality over time, The first month of treatment is a critical period for suicide risk in FEP. Although early reductions in suicidality are often maintained, our findings make the case for sustained monitoring for suicide risk management.
Identifiants
pubmed: 32986470
doi: 10.1177/0706743720961714
pmc: PMC8107949
doi:
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
468-476Subventions
Organisme : NIMH NIH HHS
ID : R01 MH093303
Pays : United States
Organisme : CIHR
ID : MCT 94189
Pays : Canada
Références
Schizophr Res. 1990 Jul-Aug;3(4):247-51
pubmed: 2278986
Schizophr Res. 2010 Jan;116(1):1-8
pubmed: 19864115
Br J Psychiatry. 2017 Dec;211(6):350-358
pubmed: 28982659
Early Interv Psychiatry. 2008 Feb;2(1):11-21
pubmed: 21352126
Eur Neuropsychopharmacol. 2015 Dec;25(12):2278-88
pubmed: 26475577
Int J Soc Psychiatry. 2012 Jan;58(1):41-6
pubmed: 20826497
Br J Psychiatry. 2015 Jun;206(6):492-500
pubmed: 25657355
J Nerv Ment Dis. 2015 May;203(5):356-64
pubmed: 25900548
Am J Psychiatry. 2018 May 1;175(5):443-452
pubmed: 29495897
BMC Psychiatry. 2015 Feb 14;15:22
pubmed: 25881022
PLoS One. 2013;8(1):e55176
pubmed: 23372832
Psychol Med. 2004 Feb;34(2):255-66
pubmed: 14982131
Br J Psychiatry Suppl. 2007 Dec;51:s140-6
pubmed: 18055932
Schizophr Res. 2010 Nov;123(2-3):257-62
pubmed: 20685083
Acta Psychiatr Scand. 2004 Feb;109(2):116-20
pubmed: 14725592
Br J Psychiatry. 2013 May;202(5):372-80
pubmed: 23520223
Schizophr Res. 2014 Aug;157(1-3):12-8
pubmed: 24976591
Schizophr Res. 2020 Aug;222:382-388
pubmed: 32507375
Psychol Med. 2018 Apr;48(5):765-776
pubmed: 28805179
Suicide Life Threat Behav. 2019 Apr;49(2):423-431
pubmed: 29444349
BMJ. 2004 Jul 31;329(7460):261
pubmed: 15213108
Arch Gen Psychiatry. 2010 Dec;67(12):1230-7
pubmed: 21135323
Psychiatry Res. 2010 Jan 30;175(1-2):98-103
pubmed: 19962766
Schizophr Res. 2018 Dec;202:347-353
pubmed: 29935885
Front Psychiatry. 2016 Jun 27;7:116
pubmed: 27445872
BMJ. 2017 Jan 12;356:i6681
pubmed: 28082379
Br J Psychiatry Suppl. 2002 Sep;43:s98-106
pubmed: 12271808
Schizophr Bull. 1998;24(4):629-34
pubmed: 9853794
Arch Gen Psychiatry. 2005 Mar;62(3):247-53
pubmed: 15753237
Am J Psychiatry. 2005 Mar;162(3):441-9
pubmed: 15741458
World Psychiatry. 2017 Oct;16(3):278-286
pubmed: 28941098
JAMA Psychiatry. 2018 May 1;75(5):458-464
pubmed: 29617517
Lancet Psychiatry. 2016 May;3(5):443-50
pubmed: 26948484