Cellular Prion Protein (PrPc): Putative Interacting Partners and Consequences of the Interaction.
cellular prion protein
gene mutations
prion diseases
protein–protein interactions
signal transduction
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
25 Sep 2020
25 Sep 2020
Historique:
received:
31
07
2020
revised:
20
09
2020
accepted:
23
09
2020
entrez:
30
9
2020
pubmed:
1
10
2020
medline:
3
3
2021
Statut:
epublish
Résumé
Cellular prion protein (PrPc) is a small glycosylphosphatidylinositol (GPI) anchored protein most abundantly found in the outer leaflet of the plasma membrane (PM) in the central nervous system (CNS). PrPc misfolding causes neurodegenerative prion diseases in the CNS. PrPc interacts with a wide range of protein partners because of the intrinsically disordered nature of the protein's N-terminus. Numerous studies have attempted to decipher the physiological role of the prion protein by searching for proteins which interact with PrPc. Biochemical characteristics and biological functions both appear to be affected by interacting protein partners. The key challenge in identifying a potential interacting partner is to demonstrate that binding to a specific ligand is necessary for cellular physiological function or malfunction. In this review, we have summarized the intracellular and extracellular interacting partners of PrPc and potential consequences of their binding. We also briefly describe prion disease-related mutations at the end of this review.
Identifiants
pubmed: 32992764
pii: ijms21197058
doi: 10.3390/ijms21197058
pmc: PMC7583789
pii:
doi:
Substances chimiques
Ligands
0
Prion Proteins
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Natural Sciences and Engineering Research Council of Canada
ID : 414612
Références
Sci China C Life Sci. 2006 Oct;49(5):473-9
pubmed: 17172055
J Neurosci. 2007 Nov 7;27(45):12331-40
pubmed: 17989297
Nat Rev Mol Cell Biol. 2008 Jan;9(1):22-32
pubmed: 18073770
Prion. 2016;10(1):63-82
pubmed: 26645475
Biochemistry. 1990 Jun 19;29(24):5848-55
pubmed: 1974464
J Biol Chem. 1998 Dec 25;273(52):35194-200
pubmed: 9857057
BMC Biol. 2017 May 2;15(1):34
pubmed: 28464931
Curr Opin Neurobiol. 2010 Oct;20(5):563-71
pubmed: 20579869
PLoS One. 2011;6(9):e25675
pubmed: 21980526
J Neurosci. 2008 Jun 25;28(26):6691-702
pubmed: 18579743
Pharmacol Rev. 2008 Dec;60(4):536-81
pubmed: 19112153
Pathogens. 2017 Nov 17;6(4):
pubmed: 29149024
Antioxid Redox Signal. 2015 Mar 20;22(9):772-84
pubmed: 25490055
Mol Neurobiol. 2016 Sep;53(7):4484-96
pubmed: 26255182
Brain Res. 1982 Jan 28;232(2):489-93
pubmed: 6765112
Cell Mol Neurobiol. 2007 Feb;27(1):107-28
pubmed: 17151946
Mol Cancer Ther. 2004 Oct;3(10):1289-99
pubmed: 15486196
PLoS Pathog. 2009 Nov;5(11):e1000666
pubmed: 19936054
J Neurol Sci. 2008 Dec 15;275(1-2):145-7
pubmed: 18706660
Acta Neuropathol. 2005 Sep;110(3):317-9
pubmed: 16025285
Mol Biol Cell. 2011 Sep;22(17):3041-54
pubmed: 21757544
Cold Spring Harb Perspect Biol. 2013 Feb 01;5(2):
pubmed: 23378584
Mol Biol Cell. 2011 Dec;22(24):4842-53
pubmed: 22031292
Cell Mol Life Sci. 2002 Oct;59(10):1640-8
pubmed: 12475174
J Neurosci. 2012 Nov 21;32(47):16857-71a
pubmed: 23175838
Brain Res. 2001 Mar 23;895(1-2):268-72
pubmed: 11259789
J Neurosci. 2008 Nov 19;28(47):12489-99
pubmed: 19020041
J Cell Sci. 2007 Jun 1;120(Pt 11):1915-26
pubmed: 17504807
Annu Rev Neurosci. 1993;16:403-43
pubmed: 7681637
Biochemistry. 1980 Aug 19;19(17):3913-8
pubmed: 7407077
Dev Cell. 2003 Oct;5(4):571-82
pubmed: 14536059
Nat Rev Neurosci. 2016 Mar;17(3):160-72
pubmed: 26891626
Biomed Rep. 2017 Feb;6(2):127-133
pubmed: 28357063
Int J Hyperthermia. 2000 May-Jun;16(3):231-45
pubmed: 10830586
Nat Rev Neurosci. 2013 Jun;14(6):383-400
pubmed: 23686171
Science. 1984 Dec 7;226(4679):1209-11
pubmed: 6438799
Exp Neurol. 2015 Sep;271:155-67
pubmed: 26024859
Cent Eur J Immunol. 2015;40(3):373-9
pubmed: 26648784
Arq Neuropsiquiatr. 2001 Jun;59(2-A):161-4
pubmed: 11400017
J Cereb Blood Flow Metab. 2009 Nov;29(11):1780-9
pubmed: 19675565
Biochim Biophys Acta. 2016 Jan;1860(1 Pt B):278-86
pubmed: 26049079
J Neurosci. 2005 Apr 27;25(17):4353-64
pubmed: 15858061
Brain Res. 1988 Jan 12;438(1-2):311-4
pubmed: 3345436
Am J Hum Genet. 2015 Jun 4;96(6):955-61
pubmed: 26004201
Trends Cell Biol. 2002 Jun;12(6):273-80
pubmed: 12074887
J Cell Biol. 2008 May 5;181(3):551-65
pubmed: 18443219
FASEB J. 2011 Jan;25(1):265-79
pubmed: 20876210
Viruses. 2019 Mar 14;11(3):
pubmed: 30875755
Neuron. 2008 Nov 26;60(4):598-609
pubmed: 19038218
Mol Biol Cell. 2006 Aug;17(8):3356-68
pubmed: 16707568
J Biol Chem. 2001 Oct 19;276(42):39145-9
pubmed: 11522774
J Neurosci. 2005 May 11;25(19):4879-88
pubmed: 15888663
Med Microbiol Immunol. 2020 Aug;209(4):427-436
pubmed: 32468130
J Cell Biol. 1995 Dec;131(6 Pt 1):1435-52
pubmed: 8522602
Mol Neurobiol. 1999 Aug;20(1):1-16
pubmed: 10595869
Front Cell Neurosci. 2014 Mar 27;8:82
pubmed: 24723849
Nat Struct Mol Biol. 2012 Apr 08;19(5):517-24, S1
pubmed: 22484317
Prion. 2018 Mar 4;12(2):117-126
pubmed: 29644924
Biochem Biophys Res Commun. 2008 Jan 4;365(1):154-7
pubmed: 17981143
J Virol. 1996 Jul;70(7):4724-8
pubmed: 8676499
Biochim Biophys Acta. 2012 Mar;1823(3):774-87
pubmed: 22079671
Prion. 2012 Jul 1;6(3):217-22
pubmed: 22449984
Annu Rev Pharmacol Toxicol. 2000;40:617-47
pubmed: 10836149
Enzyme. 1975;20(1):20-34
pubmed: 236178
J Pept Sci. 2011 May;17(5):387-91
pubmed: 21294227
J Neurosci. 2011 Dec 7;31(49):18013-25
pubmed: 22159115
Mol Neurobiol. 2018 Jul;55(7):5478-5489
pubmed: 28956310
Am J Hum Genet. 2000 Jan;66(1):110-7
pubmed: 10631141
Methods Mol Biol. 2012;757:81-99
pubmed: 21909908
Mol Biol Cell. 2007 Apr;18(4):1129-42
pubmed: 17229889
J Cell Sci. 2008 Mar 15;121(Pt 6):773-83
pubmed: 18285446
EMBO Rep. 2003 Mar;4(3):290-5
pubmed: 12634848
Proc Natl Acad Sci U S A. 2014 Jun 17;111(24):8979-84
pubmed: 24889613
Eur J Cell Biol. 2011 May;90(5):414-9
pubmed: 21277044
Dialogues Clin Neurosci. 2000 Sep;2(3):219-32
pubmed: 22034391
J Mol Biol. 2001 Dec 14;314(5):1209-25
pubmed: 11743735
Prion. 2012 Sep-Oct;6(4):334-8
pubmed: 22874672
Biochem Biophys Res Commun. 2004 Jan 16;313(3):818-23
pubmed: 14697265
Arch Virol. 2008;153(6):1013-20
pubmed: 18404245
Semin Cell Dev Biol. 1999 Oct;10(5):465-72
pubmed: 10597629
J Biol Chem. 1999 Dec 3;274(49):34846-50
pubmed: 10574957
Nature. 2009 Jun 4;459(7247):703-7
pubmed: 19404260
Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11573-7
pubmed: 8265592
Mol Cell Biol. 2007 Jan;27(1):111-9
pubmed: 17060450
Neurology. 2005 Apr 12;64(7):1304-6
pubmed: 15824374
Sci Rep. 2017 Feb 02;7:41556
pubmed: 28148964
J Comp Pathol. 1983 Apr;93(2):251-9
pubmed: 6345602
J Biomed Biotechnol. 2006;2006(5):69469
pubmed: 17489019
Adv Protein Chem. 2005;71:257-98
pubmed: 16230114
J Biol Chem. 2013 Dec 27;288(52):37241-55
pubmed: 24225951
J Physiol. 2012 Mar 15;590(6):1357-68
pubmed: 22310309
Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1737-42
pubmed: 22307640
Int J Biochem Cell Biol. 1999 May;31(5):539-44
pubmed: 10399314
Prion. 2012 Sep-Oct;6(4):354-8
pubmed: 22842913
FEBS Lett. 2005 Oct 10;579(24):5419-24
pubmed: 16198347
EMBO J. 1988 Mar;7(3):625-32
pubmed: 3396534
Nat Neurosci. 2012 Sep;15(9):1227-35
pubmed: 22820466
PLoS One. 2017 Dec 20;12(12):e0188340
pubmed: 29261664
Biochemistry. 1992 Jun 2;31(21):5043-53
pubmed: 1350920
Science. 2002 Jul 19;297(5580):353-6
pubmed: 12130773
Nature. 2000 Sep 28;407(6803):520-3
pubmed: 11029004
FASEB J. 2014 Sep;28(9):3823-31
pubmed: 24858278
J Proteome Res. 2011 Jul 1;10(7):3123-35
pubmed: 21604690
Am J Pathol. 2010 Sep;177(3):1411-21
pubmed: 20651247
Biotechnol Appl Biochem. 2008 Jan;49(Pt 1):25-33
pubmed: 17576199
Neuroscience. 1993 May;54(1):15-36
pubmed: 8515840
Proc Natl Acad Sci U S A. 2001 Feb 13;98(4):1619-24
pubmed: 11172000
IUBMB Life. 2008 Jun;60(6):390-7
pubmed: 18425793
J Cell Biol. 2005 Apr 25;169(2):341-54
pubmed: 15851519
Mol Biol Cell. 2008 May;19(5):2311-27
pubmed: 18305102
PLoS Pathog. 2009 Oct;5(10):e1000608
pubmed: 19798432
Brain Res Mol Brain Res. 1995 May;30(1):165-8
pubmed: 7609638
J Neurosci. 2005 Dec 7;25(49):11330-9
pubmed: 16339028
Neuron. 1998 Dec;21(6):1339-51
pubmed: 9883727
Handb Clin Neurol. 2018;153:243-269
pubmed: 29887140
Clin Exp Immunol. 2006 Oct;146(1):1-8
pubmed: 16968391
Neurobiol Dis. 1997;3(4):339-55
pubmed: 9173930
Nature. 1987 Jul 30-Aug 5;328(6129):378-9
pubmed: 3112578
Brain Res Mol Brain Res. 2000 Mar 10;76(1):85-92
pubmed: 10719218
Methods Enzymol. 2001;329:175-87
pubmed: 11210534
J Mol Biol. 1997 Jan 17;265(2):257
pubmed: 9020986
Front Psychiatry. 2019 Jan 24;9:767
pubmed: 30733690
Cell Tissue Res. 2006 Nov;326(2):457-82
pubmed: 16847640
EMBO J. 2001 Nov 1;20(21):5876-86
pubmed: 11689428
Cell. 1984 Aug;38(1):127-34
pubmed: 6432339
Brain Res. 1998 Nov 2;809(2):277-87
pubmed: 9853120
Genes Dev. 2004 Jul 15;18(14):1737-52
pubmed: 15256501
Am J Pathol. 2014 Jan;184(1):18-27
pubmed: 24128688
Nat Med. 1997 Dec;3(12):1383-8
pubmed: 9396609
J Neurochem. 2005 Dec;95(5):1373-86
pubmed: 16313516
Curr Opin Neurobiol. 2000 Jun;10(3):342-51
pubmed: 10851174
Genomics. 1995 Jan 20;25(2):365-71
pubmed: 7789969
Neuroscience. 1995 Sep;68(1):245-53
pubmed: 7477929
Nat Med. 1997 Dec;3(12):1376-82
pubmed: 9396608
Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13147-52
pubmed: 20615969
Biochem Biophys Res Commun. 2005 Aug 26;334(2):403-11
pubmed: 16004966
Biochem Soc Trans. 2016 Aug 15;44(4):994-1004
pubmed: 27528744
J Neurochem. 2012 Mar;120(6):853-68
pubmed: 22145935
J Neurochem. 2006 Sep;98(6):1876-85
pubmed: 16945105
Nat Rev Neurosci. 2004 Mar;5(3):195-208
pubmed: 14976519
Acta Biochim Biophys Sin (Shanghai). 2008 Dec;40(12):1039-47
pubmed: 19089302
Int J Mol Sci. 2019 Jul 23;20(14):
pubmed: 31340582
Biochem Biophys Res Commun. 1992 Oct 15;188(1):395-401
pubmed: 1417860
Nature. 1997 Nov 20;390(6657):241
pubmed: 9384372
Biochem J. 2007 Feb 15;402(1):17-23
pubmed: 17155929
Philos Trans R Soc Lond B Biol Sci. 2003 Apr 29;358(1432):773-86
pubmed: 12744273
Curr Top Microbiol Immunol. 1998;228:325-42
pubmed: 9401211
Mol Cell. 2007 Jun 8;26(5):611-23
pubmed: 17560368
Mol Cell Biochem. 2008 Mar;310(1-2):49-55
pubmed: 18038270
Nature. 1990 Feb 15;343(6259):669-72
pubmed: 1968226
Brain Res. 2010 Feb 2;1312:156-67
pubmed: 19931516
Am J Transl Res. 2019 Feb 15;11(2):520-528
pubmed: 30899359
J Biol Chem. 2001 Nov 9;276(45):42409-21
pubmed: 11527974
Mol Diagn Ther. 2009;13(4):225-44
pubmed: 19712003
Biochem Biophys Res Commun. 2005 Mar 4;328(1):14-9
pubmed: 15670743
Neuroreport. 1993 Jan;4(1):65-8
pubmed: 8453038
Front Cell Dev Biol. 2017 Apr 06;5:34
pubmed: 28428953
Neuron. 2012 Apr 26;74(2):300-13
pubmed: 22542184
J Neuropathol Exp Neurol. 2005 Oct;64(10):858-68
pubmed: 16215457
Development. 2017 Sep 1;144(17):3012-3021
pubmed: 28851722
Br J Pharmacol. 2011 Jan;162(1):175-92
pubmed: 20955365
Nat Neurosci. 2017 Nov;20(11):1569-1579
pubmed: 28945221
Front Neurosci. 2018 Nov 12;12:821
pubmed: 30483047
J Neurochem. 2003 Aug;86(3):538-44
pubmed: 12859667
Mol Cell Biol. 2003 Sep;23(18):6494-506
pubmed: 12944476
Cardiovasc Res. 2010 May 1;86(2):219-25
pubmed: 20202978
Brain. 2014 Mar;137(Pt 3):873-86
pubmed: 24519981
J Mol Neurosci. 2011 Oct;45(2):216-28
pubmed: 21301993
J Neurochem. 2000 Nov;75(5):1889-97
pubmed: 11032878
Neuron. 1995 Jan;14(1):29-41
pubmed: 7826639
Brain Res Mol Brain Res. 1996 Apr;37(1-2):249-58
pubmed: 8738158
Biochem J. 2000 Nov 15;352 Pt 1:191-6
pubmed: 11062072
Biochem Biophys Res Commun. 2012 Jan 6;417(1):182-6
pubmed: 22138399
J Neurosci Res. 2007 Sep;85(12):2741-55
pubmed: 17304577
Biochem Biophys Res Commun. 2020 Apr 30;525(2):447-454
pubmed: 32107004
EMBO J. 2001 Nov 1;20(21):5863-75
pubmed: 11689427
J Neurosci. 2009 May 20;29(20):6607-15
pubmed: 19458231
J Biol Chem. 1999 Apr 23;274(17):11736-41
pubmed: 10206989
PLoS One. 2009 Aug 04;4(8):e6497
pubmed: 19652718
J Neurochem. 2016 Feb;136(4):731-740
pubmed: 26526056
J Mol Biol. 1999 Jun 25;289(5):1163-78
pubmed: 10373359
Nature. 1997 Dec 18-25;390(6661):684-7
pubmed: 9414160
Mol Neurodegener. 2019 Jul 22;14(1):29
pubmed: 31331359
Neuron. 2013 Sep 4;79(5):887-902
pubmed: 24012003
J Biol Chem. 2005 Apr 29;280(17):17057-61
pubmed: 15668233
Biochem Biophys Res Commun. 1995 May 25;210(3):753-9
pubmed: 7763249
Prion. 2015;9(5):355-66
pubmed: 26237451
Nature. 2000 Oct 26;407(6807):971-7
pubmed: 11069170
J Neurosci. 2002 Apr 15;22(8):3144-60
pubmed: 11943817
Curr Pharm Des. 2010 Jan;16(3):323-43
pubmed: 20109142
J Neuropathol Exp Neurol. 2007 Feb;66(2):124-30
pubmed: 17278997
Annu Rev Biochem. 2002;71:511-35
pubmed: 12045105
FASEB J. 1993 Aug;7(11):1023-30
pubmed: 8370471
Viruses. 2014 Oct 20;6(10):3875-92
pubmed: 25333467
Sci Rep. 2016 Feb 11;6:21658
pubmed: 26865414
J Neurosci. 2010 May 5;30(18):6367-74
pubmed: 20445063
Nat Rev Genet. 2013 Jul;14(7):447-59
pubmed: 23732335
Biol Open. 2018 Jan 22;7(1):
pubmed: 29358166
Mol Biol Cell. 2012 May;23(10):1812-25
pubmed: 22438585
Proteins. 2009 Nov 1;77(2):279-96
pubmed: 19422054
Zhonghua Zhong Liu Za Zhi. 2013 Feb;35(2):94-7
pubmed: 23714661
Biochem J. 2015 Aug 1;469(3):347-55
pubmed: 26205490
J Bone Miner Res. 2013 Jul;28(7):1587-98
pubmed: 23427088
J Biol Chem. 2010 Aug 20;285(34):26377-83
pubmed: 20576610
Genes Dev. 2007 Oct 15;21(20):2539-44
pubmed: 17938239
Biomolecules. 2019 Dec 18;10(1):
pubmed: 31861275
Nat Neurosci. 2000 Jan;3(1):15-21
pubmed: 10607390
Prion. 2017 Jul 4;11(4):226-233
pubmed: 28759332
Bing Du Xue Bao. 2009 May;25(3):208-12
pubmed: 19634764
Proc Natl Acad Sci U S A. 2007 Jun 26;104(26):11062-7
pubmed: 17573534
J Neurosci. 2013 Feb 6;33(6):2408-18
pubmed: 23392670
J Neurochem. 2013 Jan;124(2):210-23
pubmed: 23145988
C R Seances Acad Sci III. 1981 Jul 6;293(1):53-6
pubmed: 6796203
Nat Rev Mol Cell Biol. 2013 Oct;14(10):630-42
pubmed: 24026055
Mol Biol Cell. 2009 Jun;20(12):2831-40
pubmed: 19386765
Membranes (Basel). 2014 Jul 11;4(3):356-71
pubmed: 25019426
J Biol Chem. 2011 Sep 23;286(38):33489-500
pubmed: 21795680
IUBMB Life. 2010 Apr;62(4):268-76
pubmed: 20101634
Nat Rev Mol Cell Biol. 2009 Apr;10(4):287-92
pubmed: 19277045
Matrix Biol. 1994 Apr;14(3):209-11
pubmed: 7921537
Eur Heart J. 2012 Apr;33(7):829-37, 837a-837d
pubmed: 21890489
Acta Neuropathol. 2002 Jun;103(6):615-26
pubmed: 12012094
Biochim Biophys Acta. 2011 Oct;1813(10):1845-53
pubmed: 21763357
Neurobiol Aging. 2011 May;32(5):834-44
pubmed: 19464074
Nature. 2016 Aug 25;536(7617):464-8
pubmed: 27501152
J Biol Chem. 2014 Oct 10;289(41):28460-77
pubmed: 25148681
Nat Rev Mol Cell Biol. 2009 Aug;10(8):513-25
pubmed: 19603039
Cold Spring Harb Perspect Biol. 2011 Aug 01;3(8):a003947
pubmed: 21746798
Neurotox Res. 2013 May;23(4):301-14
pubmed: 22855343
Int J Biochem Cell Biol. 2014 Feb;47:20-8
pubmed: 24269782
J Neurosci. 2011 Apr 27;31(17):6329-38
pubmed: 21525273
Nat Commun. 2014 Mar 04;5:3374
pubmed: 24594908
Nature. 2009 Feb 26;457(7233):1128-32
pubmed: 19242475
J Neurochem. 2013 Oct;127(1):124-38
pubmed: 23638794
Nat Rev Mol Cell Biol. 2001 Feb;2(2):107-17
pubmed: 11252952
Neuron. 2018 Sep 19;99(6):1155-1169.e9
pubmed: 30174115
PLoS Pathog. 2017 Nov 27;13(11):e1006733
pubmed: 29176838
J Biol Chem. 2001 Nov 30;276(48):44604-12
pubmed: 11571277
EMBO J. 2002 Jul 1;21(13):3307-16
pubmed: 12093732
Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14945-9
pubmed: 8962161
Brain Pathol. 2016 Jan;26(1):3-17
pubmed: 26269128
Mol Cell Neurosci. 2014 Nov;63:31-7
pubmed: 25242137
Front Cell Neurosci. 2018 Oct 09;12:338
pubmed: 30356756
Proc Natl Acad Sci U S A. 1975 May;72(5):1858-62
pubmed: 1057175
Biochem Biophys Res Commun. 2000 May 10;271(2):337-41
pubmed: 10799298
Cell. 1983 Nov;35(1):57-62
pubmed: 6414721
Prion. 2015;9(2):119-24
pubmed: 25746597
Brain. 1992 Jun;115 ( Pt 3):687-710
pubmed: 1352725
EMBO J. 2002 Jul 1;21(13):3317-26
pubmed: 12093733
Trends Cell Biol. 2010 Jan;20(1):6-13
pubmed: 19896850
Sci Transl Med. 2016 Jan 20;8(322):322ra9
pubmed: 26791950
Mol Neurodegener. 2011 Apr 28;6(1):27
pubmed: 21527012
J Neurosci. 1996 Apr 1;16(7):2157-63
pubmed: 8601796
Biochem Biophys Res Commun. 2004 Mar 19;315(4):802-7
pubmed: 14985083
J Neurochem. 2009 Jul;110(1):194-207
pubmed: 19457127
J Biol Chem. 2005 Apr 29;280(17):17062-7
pubmed: 15668247
J Oral Pathol Med. 2015 Jul;44(6):449-52
pubmed: 25224513
Physiol Rev. 2004 Apr;84(2):361-84
pubmed: 15044677
J Mol Biol. 2009 May 22;388(5):968-77
pubmed: 19327369
FEBS Lett. 2000 Oct 6;482(3):257-60
pubmed: 11024471
J Lipid Res. 2007 May;48(5):993-1011
pubmed: 17361015
Trends Endocrinol Metab. 2002 Mar;13(2):66-74
pubmed: 11854021
Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):435-40
pubmed: 9892651
Proc Natl Acad Sci U S A. 2008 Jan 15;105(2):512-7
pubmed: 18178619
Biochem J. 2003 Jan 1;369(Pt 1):1-15
pubmed: 12396231
Cell Death Differ. 2005 Jul;12(7):783-95
pubmed: 15846375
Neurol Sci. 2008 Dec;29(6):405-10
pubmed: 19030774
Neuron. 1996 Jul;17(1):103-13
pubmed: 8755482
Oncotarget. 2015 Sep 22;6(28):24660-74
pubmed: 26295309
Annu Rev Cell Dev Biol. 1997;13:425-56
pubmed: 9442880
Arch Biochem Biophys. 1989 Oct;274(1):1-13
pubmed: 2505674
Neurology. 2012 Oct 2;79(14):1499-506
pubmed: 22993290
Nat Rev Neurosci. 2003 Sep;4(9):752-62
pubmed: 12951567
PLoS One. 2012;7(12):e51305
pubmed: 23236467
PLoS Pathog. 2015 Apr 16;11(4):e1004796
pubmed: 25880443
PLoS One. 2013;8(1):e55575
pubmed: 23383230
Science. 1982 Apr 9;216(4542):136-44
pubmed: 6801762
J Neurosci. 2016 Dec 7;36(49):12351-12367
pubmed: 27927955
Mol Biol Cell. 2015 Sep 15;26(18):3313-28
pubmed: 26224313
J Biol Chem. 2010 Nov 19;285(47):36542-50
pubmed: 20837487
Biochemistry. 2004 Aug 17;43(32):10393-9
pubmed: 15301538
Arch Biochem Biophys. 2008 Feb 1;470(1):83-92
pubmed: 18037369
Cell Signal. 2006 Mar;18(3):267-75
pubmed: 16126370
J Biol Chem. 2002 Dec 13;277(50):48043-50
pubmed: 12376548
Ann Med Surg (Lond). 2014 Jul 23;3(3):77-81
pubmed: 25568792
Physiol Rev. 2008 Apr;88(2):673-728
pubmed: 18391177
Arch Virol. 1997;142(12):2537-45
pubmed: 9672613
Mol Cell Neurosci. 2005 Jun;29(2):232-44
pubmed: 15911347
Brain Res. 1997 Jan 2;744(1):105-11
pubmed: 9030418
Med Microbiol Immunol. 2008 Dec;197(4):361-8
pubmed: 18087720
J Biol Chem. 2003 Sep 26;278(39):37241-8
pubmed: 12865430
Sci Rep. 2014 May 08;4:4881
pubmed: 24810941
J Mol Biol. 2001 Nov 2;313(4):889-901
pubmed: 11697911
FASEB J. 2012 Feb;26(2):678-90
pubmed: 22038049
Acta Neuropathol. 2003 Mar;105(3):296-302
pubmed: 12557018
Curr Opin Neurobiol. 2012 Jun;22(3):496-508
pubmed: 22325859
J Biol Chem. 2013 Mar 29;288(13):8935-51
pubmed: 23386614
Acta Biochim Biophys Sin (Shanghai). 2006 Sep;38(9):593-601
pubmed: 16953297
Proteomics. 2006 Jan;6(1):26-34
pubmed: 16294306
J Neurosci. 2013 Oct 16;33(42):16552-64
pubmed: 24133259