Fully self-gated whole-heart 4D flow imaging from a 5-minute scan.


Journal

Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245

Informations de publication

Date de publication:
03 2021
Historique:
received: 17 02 2020
revised: 20 07 2020
accepted: 01 08 2020
pubmed: 1 10 2020
medline: 15 5 2021
entrez: 30 9 2020
Statut: ppublish

Résumé

To develop and validate an acquisition and processing technique that enables fully self-gated 4D flow imaging with whole-heart coverage in a fixed 5-minute scan. The data are acquired continuously using Cartesian sampling and sorted into respiratory and cardiac bins using the self-gating signal. The reconstruction is performed using a recently proposed Bayesian method called ReVEAL4D. ReVEAL4D is validated using data from 8 healthy volunteers and 2 patients and compared with compressed sensing technique, L1-SENSE. Healthy subjects-Compared with 2D phase-contrast MRI (2D-PC), flow quantification from ReVEAL4D shows no significant bias. In contrast, the peak velocity and peak flow rate for L1-SENSE are significantly underestimated. Compared with traditional parallel MRI-based 4D flow imaging, ReVEAL4D demonstrates small but significant biases in net flow and peak flow rate, with no significant bias in peak velocity. All 3 indices are significantly and more markedly underestimated by L1-SENSE. Patients-Flow quantification from ReVEAL4D agrees well with the 2D-PC reference. In contrast, L1-SENSE markedly underestimated peak velocity. The combination of highly accelerated 5-minute Cartesian acquisition, self-gating, and ReVEAL4D enables whole-heart 4D flow imaging with accurate flow quantification.

Identifiants

pubmed: 32996625
doi: 10.1002/mrm.28491
pmc: PMC7718421
mid: NIHMS1630002
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

1222-1236

Subventions

Organisme : NHLBI NIH HHS
ID : R01 HL135489
Pays : United States
Organisme : NIBIB NIH HHS
ID : R21 EB026657
Pays : United States

Informations de copyright

© 2020 International Society for Magnetic Resonance in Medicine.

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Auteurs

Aaron Pruitt (A)

Biomedical Engineering, The Ohio State University, Columbus, OH, USA.

Adam Rich (A)

Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Electrical and Computer Engineering, The Ohio State University, Columbus, OH, USA.

Yingmin Liu (Y)

Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.

Ning Jin (N)

Cardiovascular MR R&D, Siemens Medical Solutions USA Inc., Columbus, OH, USA.

Lee Potter (L)

Electrical and Computer Engineering, The Ohio State University, Columbus, OH, USA.
Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.

Matthew Tong (M)

Internal Medicine, The Ohio State University, Columbus, OH, USA.

Saurabh Rajpal (S)

Internal Medicine, The Ohio State University, Columbus, OH, USA.

Orlando Simonetti (O)

Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.
Internal Medicine, The Ohio State University, Columbus, OH, USA.
Radiology, The Ohio State University, Columbus, OH, USA.

Rizwan Ahmad (R)

Biomedical Engineering, The Ohio State University, Columbus, OH, USA.
Electrical and Computer Engineering, The Ohio State University, Columbus, OH, USA.
Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA.

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