Associations of aging trajectories for an index of frailty score with mortality and medical and long-term care costs among older Japanese undergoing health checkups.
Aged
Aged, 80 and over
Aging
/ psychology
Cardiovascular Diseases
/ mortality
Cause of Death
Female
Frail Elderly
Frailty
/ epidemiology
Geriatric Assessment
Health Care Costs
/ statistics & numerical data
Humans
Independent Living
Japan
/ epidemiology
Long-Term Care
/ economics
Male
Proportional Hazards Models
Prospective Studies
frailty
long-term care costs
medical costs
mortality
trajectories
Journal
Geriatrics & gerontology international
ISSN: 1447-0594
Titre abrégé: Geriatr Gerontol Int
Pays: Japan
ID NLM: 101135738
Informations de publication
Date de publication:
Nov 2020
Nov 2020
Historique:
received:
18
06
2020
revised:
16
08
2020
accepted:
14
09
2020
pubmed:
1
10
2020
medline:
1
12
2020
entrez:
30
9
2020
Statut:
ppublish
Résumé
Using up to 13 years of repeated-measures data, we identified aging trajectories for an index in frailty score among older Japanese undergoing health checkups. In addition, we examined whether these trajectories were associated with all-cause and cause-specific mortality and healthcare costs. In total, 1698 adults aged ≥65 years completed annual assessments during 2002-2014. During follow-up, the average number of follow-up assessments was 3.9, and the total number of observations was 6373. Frailty was defined by using the following criteria from Fried's phenotype: slowness, weakness, exhaustion, low physical activity and weight loss. We identified four aging trajectories for frailty. Specifically, 6.5%, 47.3%, 30.3% and 16.0% of participants were in the high, second, third and low trajectory groups, respectively. As compared with the low trajectory group, the high trajectory group had greater risks of cardiovascular disease (adjusted hazard ratios of 3.42) and other-cause death (adjusted hazard ratios of 3.04). The high trajectory group had the highest medical costs until late in the eighth decade of life, costs decreased after age 70 years and were lowest at age 90 years (estimated at $116.7); however, medical and long-term care costs greatly increased after age 80 years in the second and third trajectory groups. Higher aging trajectories in frailty score were associated with elevated risks for cardiovascular, other-cause and all-cause death among older Japanese receiving health checkups. Medical and care needs greatly increased for the second and third trajectory groups when their frailty level was progressed in later life. Geriatr Gerontol Int 2020; 20: 1072-1078..
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1072-1078Subventions
Organisme : Grant-In-Aid for Research Activity Start-up
ID : JP24890302
Organisme : Grants-In-Aid for Scientific Research
ID : (B) JP20390190
Organisme : Grants-In-Aid for Scientific Research
ID : (B) JP21390212
Organisme : Grants-In-Aid for Scientific Research
ID : (B) JP24390173
Organisme : Grants-In-Aid for Scientific Research
ID : (B) JP26310111
Organisme : Grants-In-Aid for Young Scientists
ID : (B) JP15K16539
Organisme : Grants-In-Aid for Young Scientists
ID : 18K17409
Informations de copyright
© 2020 Japan Geriatrics Society.
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