The utilization of buprenorphine in chronic pain.
buprenorphine
chronic pain
opioids
pain control
partial agonist
Journal
Best practice & research. Clinical anaesthesiology
ISSN: 1878-1608
Titre abrégé: Best Pract Res Clin Anaesthesiol
Pays: Netherlands
ID NLM: 101121446
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
30
06
2020
accepted:
30
06
2020
entrez:
2
10
2020
pubmed:
3
10
2020
medline:
2
6
2021
Statut:
ppublish
Résumé
Reclassification of chronic pain as a disease may be helpful because patients with chronic pain require significant treatment and rehabilitation with a clear diagnosis. This can help address critical factors including suffering, quality of life, participation, and with family and social life, which continue to become more important in evaluating the quality of the health care we give our patients today. During the past decade of the opioid epidemic, methadone was the primary treatment for opioid addiction until buprenorphine was approved. Buprenorphine's high-affinity partial agonist properties make it a good alternative to methadone due to lower abuse potential and safer adverse effect profile while maintaining significant efficacy. Expanded out-patient prescribing options have allowed physician and physician extenders such as physician assistants and nurse practitioners to treat these patients that otherwise would have been required to utilize methadone. With unique pharmacological properties, buprenorphine is a safe and effective analgesic for chronic pain. The literature for buprenorphine shows great potential for its utilization in the treatment of chronic pain.
Identifiants
pubmed: 33004153
pii: S1521-6896(20)30046-X
doi: 10.1016/j.bpa.2020.06.005
pii:
doi:
Substances chimiques
Analgesics, Opioid
0
Buprenorphine
40D3SCR4GZ
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
355-368Informations de copyright
Copyright © 2020. Published by Elsevier Ltd.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors of this manuscript have no conflicts of interest to disclose.