Development and Validation Clinician and Patient Reported Photonumeric Scales to Assess Buttocks Cellulite Severity.


Journal

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
ISSN: 1524-4725
Titre abrégé: Dermatol Surg
Pays: United States
ID NLM: 9504371

Informations de publication

Date de publication:
12 2020
Historique:
pubmed: 4 10 2020
medline: 20 1 2021
entrez: 3 10 2020
Statut: ppublish

Résumé

The Clinician Reported Photonumeric Cellulite Severity Scale (CR-PCSS) and Patient Reported PCSS (PR-PCSS) are newly developed tools for assessing cellulite severity. To report on the reliability, validity, and ability to detect a change in cellulite severity on the buttocks of adult women with the CR-PCSS and PR-PCSS. Content validity of both scales was established through concept elicitation and cognitive interviews. Test-retest reliability was evaluated, and intra-rater (both scales) and inter-rater (CR-PCSS only) reliability were estimated using intraclass correlation coefficients (ICCs) for agreement and consistency. Ability to detect a change was determined using the Subject-Global Aesthetic Improvement Scale (GAIS) or Investigator-GAIS as anchors. For the CR-PCSS (n = 6) at baseline and Day 2, the mean interrater ICCs were ≥0.70 and mean intrarater ICCs (95% confidence interval [CI]) were ≥0.81 (0.72-0.90) for both buttocks. For the PR-PCSS (n = 99) at baseline and Day 14, the mean test-retest reliability ICCs (95% CI) were ≥0.86 (0.79-0.91) for both buttocks. A clinically meaningful change was 1.0 point on the PR-PCSS and 1.0 on the CR-PCSS. The CR-PCSS and PR-PCSS reliably assess cellulite severity of the buttocks and can detect a clinically meaningful change after treatment for cellulite.

Sections du résumé

BACKGROUND
The Clinician Reported Photonumeric Cellulite Severity Scale (CR-PCSS) and Patient Reported PCSS (PR-PCSS) are newly developed tools for assessing cellulite severity.
OBJECTIVE
To report on the reliability, validity, and ability to detect a change in cellulite severity on the buttocks of adult women with the CR-PCSS and PR-PCSS.
MATERIALS AND METHODS
Content validity of both scales was established through concept elicitation and cognitive interviews. Test-retest reliability was evaluated, and intra-rater (both scales) and inter-rater (CR-PCSS only) reliability were estimated using intraclass correlation coefficients (ICCs) for agreement and consistency. Ability to detect a change was determined using the Subject-Global Aesthetic Improvement Scale (GAIS) or Investigator-GAIS as anchors.
RESULTS
For the CR-PCSS (n = 6) at baseline and Day 2, the mean interrater ICCs were ≥0.70 and mean intrarater ICCs (95% confidence interval [CI]) were ≥0.81 (0.72-0.90) for both buttocks. For the PR-PCSS (n = 99) at baseline and Day 14, the mean test-retest reliability ICCs (95% CI) were ≥0.86 (0.79-0.91) for both buttocks. A clinically meaningful change was 1.0 point on the PR-PCSS and 1.0 on the CR-PCSS.
CONCLUSION
The CR-PCSS and PR-PCSS reliably assess cellulite severity of the buttocks and can detect a clinically meaningful change after treatment for cellulite.

Identifiants

pubmed: 33009069
doi: 10.1097/DSS.0000000000002756
pmc: PMC7685927
pii: 00042728-202012000-00036
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

1628-1635

Commentaires et corrections

Type : ErratumIn

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Auteurs

Joel L Cohen (JL)

AboutSkin Dermatology and DermSurgery, PC, Greenwood Village, Colorado.
Dermatology, University of California, Irvine, California.

Neil S Sadick (NS)

Department of Dermatology, Weill Cornell Medical College, Cornell University, New York, New York.

M Todd Kirby (MT)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

Michael P McLane (MP)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

William R Lenderking (WR)

Evidera, Bethesda, Maryland.

Randall H Bender (RH)

Evidera, Bethesda, Maryland.
Department of Anesthesiology, University of North Carolina, Chapel Hill, North Carolina.

Jun Chen (J)

Evidera, Bethesda, Maryland.

David Hurley (D)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

Naomi B Knoble (NB)

Evidera, Bethesda, Maryland.

Genzhou Liu (G)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

Qinfang Xiang (Q)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

Jeffrey A Davidson (JA)

Endo Pharmaceuticals, Inc., Malvern, Pennsylvania.

Mitchel P Goldman (MP)

Cosmetic Laser Dermatology: A West Dermatology Company and Volunteer Clinical Professor of Dermatology, University of California, San Diego, California.

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