Respiratory Health and Inflammatory Markers-Exposure to Cobalt in the Swedish Hard Metal Industry.
Journal
Journal of occupational and environmental medicine
ISSN: 1536-5948
Titre abrégé: J Occup Environ Med
Pays: United States
ID NLM: 9504688
Informations de publication
Date de publication:
10 2020
10 2020
Historique:
entrez:
3
10
2020
pubmed:
4
10
2020
medline:
7
8
2021
Statut:
ppublish
Résumé
To study the relationship between inhalable dust and cobalt, and respiratory symptoms, lung function, exhaled nitric oxide in expired air, and CC16 in the Swedish hard metal industry. Personal sampling of inhalable dust and cobalt, and medical examination including blood sampling was performed for 72 workers. Exposure-response relationships were determined using logistic, linear, and mixed-model analysis. The average inhalable dust and cobalt concentrations were 0.079 and 0.0017 mg/m, respectively. Statistically significant increased serum levels of CC16 were determined when the high and low cumulative exposures for cobalt were compared. Nonsignificant exposure-response relationships were observed between cross-shift inhalable dust or cobalt exposures and asthma, nose dripping, and bronchitis. Our findings suggest an exposure-response relationship between inhalable cumulative cobalt exposure and CC16 levels in blood, which may reflect an injury or a reparation process in the lungs.
Identifiants
pubmed: 33009343
doi: 10.1097/JOM.0000000000001952
pii: 00043764-202010000-00008
doi:
Substances chimiques
Air Pollutants, Occupational
0
Alloys
0
Dust
0
hard metal
0
Cobalt
3G0H8C9362
Tungsten
V9306CXO6G
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
820-829Références
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