High-resolution MRI of mummified tissues using advanced short-T

HYFI ZTE ancient Egyptian mummy high resolution high-performance gradient short T2

Journal

Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245

Informations de publication

Date de publication:
03 2021
Historique:
received: 06 07 2020
revised: 01 09 2020
accepted: 02 09 2020
pubmed: 4 10 2020
medline: 15 5 2021
entrez: 3 10 2020
Statut: ppublish

Résumé

Evolutionary medicine aims to study disease development from a long-term perspective, and through the analysis of mummified tissue, timescales of several thousand years are unlocked. Due to the status of mummies as ancient relics, noninvasive techniques are preferable, and, currently, CT imaging is the most widespread method. However, CT images lack soft-tissue contrast, making complementary MRI data desirable. Unfortunately, the dehydrated nature and short T The zero-TE-based hybrid filling technique, together with a high-performance magnetic field gradient, was used to image three ancient Egyptian mummified human body parts: a hand, a foot, and a head. A similar pairing has already been shown to increase resolution and image quality in MRI of short-T MRI images of yet unparalleled image quality were obtained for all samples, reaching isotropic resolutions of 0.6 mm and SNR values above 100. The same general features as present in CT images were depicted but with different contrast, particularly for regions containing embalming substances. Mummy MRI is a potentially valuable tool for (paleo)pathological studies, as well as for investigations into ancient mummification processes. The results presented here show sufficient improvement in the depiction of mummified tissues to clear new paths for the exploration of this field.

Identifiants

pubmed: 33009877
doi: 10.1002/mrm.28530
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1481-1492

Informations de copyright

© 2020 International Society for Magnetic Resonance in Medicine.

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Auteurs

Emily Louise Baadsvik (EL)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

Markus Weiger (M)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

Romain Froidevaux (R)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

Manuela Barbara Rösler (MB)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

David Otto Brunner (DO)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

Lena Öhrström (L)

Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.

Frank Jakobus Rühli (FJ)

Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.

Patrick Eppenberger (P)

Institute of Evolutionary Medicine, University of Zurich, Zurich, Switzerland.

Klaas Paul Pruessmann (KP)

Institute for Biomedical Engineering, ETH Zurich and University of Zurich, Zurich, Switzerland.

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