Ensuring Patient Protections When Tapering Opioids: Consensus Panel Recommendations.


Journal

Mayo Clinic proceedings
ISSN: 1942-5546
Titre abrégé: Mayo Clin Proc
Pays: England
ID NLM: 0405543

Informations de publication

Date de publication:
10 2020
Historique:
received: 01 02 2020
revised: 17 04 2020
accepted: 22 04 2020
entrez: 5 10 2020
pubmed: 6 10 2020
medline: 17 12 2020
Statut: ppublish

Résumé

Long-term opioid therapy has the potential for serious adverse outcomes and is often used in a vulnerable population. Because adverse effects or failure to maintain benefits is common with long-term use, opioid taper or discontinuation may be indicated in certain patients. Concerns about the adverse individual and population effects of opioids have led to numerous strategies aimed at reductions in prescribing. Although opioid reduction efforts have had generally beneficial effects, there have been unintended consequences. Abrupt reduction or discontinuation has been associated with harms that include serious withdrawal symptoms, psychological distress, self-medicating with illicit substances, uncontrolled pain, and suicide. Key questions remain about when and how to safely reduce or discontinue opioids in different patient populations. Thus, health care professionals who reduce or discontinue long-term opioid therapy require a clear understanding of the associated benefits and risks as well as guidance on the best practices for safe and effective opioid reduction. An interdisciplinary panel of pain clinicians and one patient advocate formulated recommendations on tapering methods and ongoing pain management in primary care with emphasis on patient-centered, integrated, comprehensive treatment models employing a biopsychosocial perspective.

Identifiants

pubmed: 33012347
pii: S0025-6196(20)30395-5
doi: 10.1016/j.mayocp.2020.04.025
pii:
doi:

Substances chimiques

Analgesics, Opioid 0

Types de publication

Consensus Development Conference Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2155-2171

Informations de copyright

Copyright © 2020 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

Auteurs

Edward C Covington (EC)

Neurological Center for Pain (Emeritus), Cleveland Clinic, Cleveland, OH. Electronic address: covinge@gmail.com.

Charles E Argoff (CE)

Comprehensive Pain Center, Albany Medical College, Albany, NY.

Jane C Ballantyne (JC)

Department of Anesthesiology and Pain Medicine, University of Washington, Seattle.

Penney Cowan (P)

American Chronic Pain Association, Rocklin, CA.

Halena M Gazelka (HM)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.

W Michael Hooten (WM)

Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, MN.

Stefan G Kertesz (SG)

Birmingham Veterans Affairs Medical Center and Division of Preventive Medicine, University of Alabama School of Medicine, Birmingham, AL.

Ajay Manhapra (A)

Department of Psychiatry, Yale University School of Medicine, New Haven, CT; New England Mental Illness Research and Education Center, West Haven, CT; Advanced Pain Clinic, Hampton VA Medical Center, Hampton, VA.

Jennifer L Murphy (JL)

James A. Haley Veterans Hospital and Department of Neurology, University of South Florida Morsani College of Medicine, Tampa.

Steven P Stanos (SP)

Swedish Pain Services, Swedish Health System, Seattle, WA.

Mark D Sullivan (MD)

Department of Psychiatry and Behavioral Sciences, Department of Anesthesiology and Pain Medicine, and Department of Bioethics and Humanities, University of Washington School of Medicine, Seattle, WA.

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Classifications MeSH