BCG vaccination: An update on current Australian practices.


Journal

Australian journal of general practice
ISSN: 2208-7958
Titre abrégé: Aust J Gen Pract
Pays: Australia
ID NLM: 101718099

Informations de publication

Date de publication:
10 2020
Historique:
entrez: 5 10 2020
pubmed: 6 10 2020
medline: 25 6 2021
Statut: ppublish

Résumé

The Bacille Calmette-Guérin (BCG) vaccine is primarily used to prevent tuberculosis (TB) infection and disease in settings with high TB incidence. The aim of this review article is to describe the current uses of BCG vaccination in Australia, including the indications and contraindications, efficacy and other off-target effects, and the role of the general practitioner. BCG vaccination in Australia is primarily used to prevent TB in neonates and children with a high risk of TB exposure. The BCG vaccine is most effective at preventing severe disseminated TB disease in young children and has variable efficacy in preventing adult disease. The BCG vaccine is usually well tolerated; however, given the small risk of adverse effects, vaccination should be undertaken by a practitioner experienced in its administration. When indicated, the BCG vaccine is available from specialist TB or travel medicine centres.

Sections du résumé

BACKGROUND
The Bacille Calmette-Guérin (BCG) vaccine is primarily used to prevent tuberculosis (TB) infection and disease in settings with high TB incidence.
OBJECTIVE
The aim of this review article is to describe the current uses of BCG vaccination in Australia, including the indications and contraindications, efficacy and other off-target effects, and the role of the general practitioner.
DISCUSSION
BCG vaccination in Australia is primarily used to prevent TB in neonates and children with a high risk of TB exposure. The BCG vaccine is most effective at preventing severe disseminated TB disease in young children and has variable efficacy in preventing adult disease. The BCG vaccine is usually well tolerated; however, given the small risk of adverse effects, vaccination should be undertaken by a practitioner experienced in its administration. When indicated, the BCG vaccine is available from specialist TB or travel medicine centres.

Identifiants

pubmed: 33015679
doi: 10.31128/AJGP-06-20-5490
doi:

Substances chimiques

Antitubercular Agents 0
BCG Vaccine 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

651-655

Auteurs

Jemma Wittner Taylor (JW)

BBNSc, MBBS, DTMH, Infectious Diseases Advanced Trainee, The Royal Melbourne Hospital, Vic.

Nigel Curtis (N)

MA, MBBS, DCH, DTM@H, FRCPCH, PhD, Professor of Paediatric Infectious Diseases, Department of Paediatrics, The University of Melbourne, Vic; Leader of Infectious Diseases Group, Murdoch Children@s Research Institute, Vic; Head of Infectious Diseases Unit, The Royal Children@s Hospital Melbourne, Vic.

Justin Denholm (J)

BMed, MBioethics, MPH+TM, PhD,@FRACP, Medical Director, Victorian Tuberculosis@Program, Vic; Principle Investigator, Doherty Institute, The University of Melbourne, Vic.

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Classifications MeSH