Outcome Disparities Among Men and Women With COVID-19: An Analysis of the New York City Population Cohort.
Adult
Aged
COVID-19
COVID-19 Testing
Cause of Death
Clinical Laboratory Techniques
/ statistics & numerical data
Cohort Studies
Coronavirus Infections
/ diagnosis
Databases, Factual
Female
Health Status Disparities
Healthcare Disparities
/ statistics & numerical data
Hospital Mortality
/ trends
Hospitalization
/ statistics & numerical data
Humans
Male
Middle Aged
New York City
Outcome Assessment, Health Care
Pandemics
/ prevention & control
Pneumonia, Viral
/ epidemiology
Retrospective Studies
Risk Assessment
Sex Factors
Journal
Journal of drugs in dermatology : JDD
ISSN: 1545-9616
Titre abrégé: J Drugs Dermatol
Pays: United States
ID NLM: 101160020
Informations de publication
Date de publication:
01 10 2020
01 10 2020
Historique:
entrez:
7
10
2020
pubmed:
8
10
2020
medline:
21
10
2020
Statut:
ppublish
Résumé
Growing evidence suggests a possible sex disparity in COVID-19 disease related outcomes. To explore the sex disparity in COVID-19 cases and outcomes using New York City (NYC) population level data. NYC surveillance data from February 29 to June 12, 2020. Individuals tested for COVID-19 in metropolitan NYC.Outcome Measurements and Statistical Analysis: Outcomes of interest included rates of COVID-19 case positivity, hospitalization and death. Relative risks and case fatality rates were computed for all outcomes based on sex and were stratified by age groups. 911,310 individuals were included, of whom 434,273 (47.65%) were male and 477,037 (52.35%) were female. Men represented the majority of positive cases (n=106,275, 51.36%), a majority of hospitalizations (n=29,847, 56.44%), and a majority of deaths (n=13,054, 59.23%). Following population level adjustments for age and sex, testing rates of men and women were equivalent. The majority of positive cases and hospitalizations occurred in men for all age groups except age >75 years, and death was more likely in men of all age groups. Men were at a statistically significant greater relative risk of case positivity, hospitalization, and death across all age groups except those <18 years of age. The most significant difference for case positivity was observed in the 65–74 age group (RR 1.22, 95%CI 1.19–1.24), for hospitalization in the 45–65 age group (RR 1.85, 95% 1.80–1.90), and for death in the 18–44 age group (RR 3.30, 95% CI 2.82–3.87). Case fatality rates were greater for men in all age-matched comparisons to women. Limitations include the use of an evolving surveillance data set and absence of further demographic characteristics such as ethnographic data. Men have higher rates of COVID-19 positivity, hospitalization, and death despite greater testing of women; this trend remains after stratification by age. J Drugs Dermatol. 2020;19(10):960-967. doi:10.36849/JDD.2020.5590.
Sections du résumé
BACKGROUND
Growing evidence suggests a possible sex disparity in COVID-19 disease related outcomes.
OBJECTIVE
To explore the sex disparity in COVID-19 cases and outcomes using New York City (NYC) population level data.
SETTING
NYC surveillance data from February 29 to June 12, 2020.
PARTICIPANTS
Individuals tested for COVID-19 in metropolitan NYC.Outcome Measurements and Statistical Analysis: Outcomes of interest included rates of COVID-19 case positivity, hospitalization and death. Relative risks and case fatality rates were computed for all outcomes based on sex and were stratified by age groups.
RESULTS AND LIMITATIONS
911,310 individuals were included, of whom 434,273 (47.65%) were male and 477,037 (52.35%) were female. Men represented the majority of positive cases (n=106,275, 51.36%), a majority of hospitalizations (n=29,847, 56.44%), and a majority of deaths (n=13,054, 59.23%). Following population level adjustments for age and sex, testing rates of men and women were equivalent. The majority of positive cases and hospitalizations occurred in men for all age groups except age >75 years, and death was more likely in men of all age groups. Men were at a statistically significant greater relative risk of case positivity, hospitalization, and death across all age groups except those <18 years of age. The most significant difference for case positivity was observed in the 65–74 age group (RR 1.22, 95%CI 1.19–1.24), for hospitalization in the 45–65 age group (RR 1.85, 95% 1.80–1.90), and for death in the 18–44 age group (RR 3.30, 95% CI 2.82–3.87). Case fatality rates were greater for men in all age-matched comparisons to women. Limitations include the use of an evolving surveillance data set and absence of further demographic characteristics such as ethnographic data.
CONCLUSION
Men have higher rates of COVID-19 positivity, hospitalization, and death despite greater testing of women; this trend remains after stratification by age. J Drugs Dermatol. 2020;19(10):960-967. doi:10.36849/JDD.2020.5590.
Identifiants
pubmed: 33026775
pii: S1545961620P0960X
doi: 10.36849/JDD.2020.5590
doi:
Types de publication
Comparative Study
Journal Article
Langues
eng
Sous-ensembles de citation
IM