Studies on the chemical constituents and quality evaluation of Rosa cymosa Tratt. root.
Rose cymosa root
chemical compositions
quantification
triterpenoids
Journal
Journal of separation science
ISSN: 1615-9314
Titre abrégé: J Sep Sci
Pays: Germany
ID NLM: 101088554
Informations de publication
Date de publication:
Dec 2020
Dec 2020
Historique:
received:
30
01
2020
revised:
03
10
2020
accepted:
04
10
2020
pubmed:
9
10
2020
medline:
21
9
2021
entrez:
8
10
2020
Statut:
ppublish
Résumé
Nowadays, the root of Rose cymosa Tratt. (Rosaceae) is widely used in clinic as one of the sources of Chinese herb medicine Jinyinggen. However, only few studies have been done on its chemical composition and quality control. In this study, 27 monomeric compounds were obtained from the ethanol extract of the roots of R. cymosa Tratt., including two undescribed triterpenes, one of which contains a distinctive contracted five-membered A-ring ursane-type skeleton and the other is a common ursane-type tritepene. Then, triterpenoids, the main components of the R. cymosa root, were qualitatively and quantitatively analyzed by thin-layer chromatography and high-performance liquid chromatography methods. Thin-layer chromatography can identify seven triterpenoids in R. cymosa Tratt. spontaneously. For the high-performance liquid chromatography fingerprint, total of 16 chromatographic peaks were selected as the common peaks of 20 batches of samples, ten of which were identified by reference substances. At the same chromatographic condition, five abundant triterpenoids were quantitatively assayed. R. cymose, as one of the origins of Jinyinggen, was similar to R. laevigata in triterpenoids compounds, which demonstrated that both of them could be used in the clinical medication. These work also laid a foundation for the further research and development of triterpenoids in R. cymosa root.
Identifiants
pubmed: 33030303
doi: 10.1002/jssc.202000005
doi:
Substances chimiques
Drugs, Chinese Herbal
0
Plant Extracts
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
4379-4389Subventions
Organisme : Major International S&T Cooperation Project from Ministry of Science and Technology of the People's Republic of China
Organisme : National Standardization Project of Traditional Chinese Medicine
Organisme : Fundamental Research Funds for the Central public welfare research institutes
Informations de copyright
© 2020 Wiley-VCH GmbH.
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