Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness.
Animals
Astrocytes
/ metabolism
Calcium Channels, L-Type
/ genetics
Connexin 30
/ genetics
Connexin 43
/ genetics
Deafness
/ congenital
Disease Models, Animal
Gap Junctions
/ metabolism
Gene Expression Regulation
Immunohistochemistry
Membrane Proteins
/ genetics
Mice
Mice, Knockout
Superior Olivary Complex
/ metabolism
astrocytes
auditory brainstem
deafness
gap junctions
lateral superior olive
otoferlin
spontaneous activity
voltage-activated calcium channel 1.3
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
06 Oct 2020
06 Oct 2020
Historique:
received:
21
08
2020
revised:
01
10
2020
accepted:
02
10
2020
entrez:
10
10
2020
pubmed:
11
10
2020
medline:
3
3
2021
Statut:
epublish
Résumé
Anisotropic gap junctional coupling is a distinct feature of astrocytes in many brain regions. In the lateral superior olive (LSO), astrocytic networks are anisotropic and oriented orthogonally to the tonotopic axis. In Ca
Identifiants
pubmed: 33036242
pii: ijms21197376
doi: 10.3390/ijms21197376
pmc: PMC7582522
pii:
doi:
Substances chimiques
Cacna1d protein, mouse
0
Calcium Channels, L-Type
0
Connexin 30
0
Connexin 43
0
Gjb6 protein, mouse
0
Membrane Proteins
0
otoferlin protein, mouse
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Deutsche Forschungsgemeinschaft
ID : STE 2352/2-1
Organisme : Deutsche Forschungsgemeinschaft
ID : RO 2327/8-2
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