Ostarine and Ligandrol Improve Muscle Tissue in an Ovariectomized Rat Model.
ligandrol
muscle correspondence
ostarine
ovariectomized rats
postmenopausal osteoporosis
selective androgen receptor modulators (SARMs)
Journal
Frontiers in endocrinology
ISSN: 1664-2392
Titre abrégé: Front Endocrinol (Lausanne)
Pays: Switzerland
ID NLM: 101555782
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
05
2020
accepted:
17
08
2020
entrez:
12
10
2020
pubmed:
13
10
2020
medline:
27
5
2021
Statut:
epublish
Résumé
In postmenopausal women, hormonal decline changes muscle function and structure. The non-steroidal selective androgen receptor modulators (SARMs) Ostarine (OS) and Ligandrol (LG) have been shown to increase muscle mass and physical function while showing a relative low risk profile. Information about their effects on muscle structure and metabolism is lacking. To analyze this, two experiments were performed using ovariectomized rats as a standard model for postmenopausal conditions. In each experiment, 3-month old Sprague-Dawley rats were divided into five groups (
Identifiants
pubmed: 33042018
doi: 10.3389/fendo.2020.556581
pmc: PMC7528560
doi:
Substances chimiques
Anilides
0
Receptors, Androgen
0
L-Lactate Dehydrogenase
EC 1.1.1.27
Citrate (si)-Synthase
EC 2.3.3.1
ostarine
O3571H3R8N
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
556581Informations de copyright
Copyright © 2020 Roch, Henkies, Carstens, Krischek, Lehmann, Komrakova and Sehmisch.
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