Atg8-mediated super-assembly of Atg40 induces local ER remodeling in reticulophagy.


Journal

Autophagy
ISSN: 1554-8635
Titre abrégé: Autophagy
Pays: United States
ID NLM: 101265188

Informations de publication

Date de publication:
12 2020
Historique:
pubmed: 13 10 2020
medline: 29 12 2020
entrez: 12 10 2020
Statut: ppublish

Résumé

Reticulophagy (or ER-phagy) is a type of selective autophagy that targets the endoplasmic reticulum (ER). In the process of reticulophagy, part of the ER is fragmented and packed within autophagosomes. However, the underlying mechanism that induces this local remodeling of ER subdomains was poorly understood. Our recent study showed that in the budding yeast

Identifiants

pubmed: 33043769
doi: 10.1080/15548627.2020.1831801
pmc: PMC7751648
doi:

Substances chimiques

ATG8 protein, S cerevisiae 0
Atg40 protein, S cerevisiae 0
Autophagy-Related Protein 8 Family 0
Autophagy-Related Proteins 0
Receptors, Cytoplasmic and Nuclear 0
Saccharomyces cerevisiae Proteins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

2299-2300

Commentaires et corrections

Type : CommentOn

Références

Nat Commun. 2020 Jul 3;11(1):3306
pubmed: 32620754

Auteurs

Keisuke Mochida (K)

School of Life Science and Technology, Tokyo Institute of Technology , Yokohama, Japan.

Hitoshi Nakatogawa (H)

School of Life Science and Technology, Tokyo Institute of Technology , Yokohama, Japan.

Articles similaires

Animals TOR Serine-Threonine Kinases Colorectal Neoplasms Colitis Mice
Animals Dogs Dog Diseases Autophagy Immunohistochemistry
Adenosine Triphosphate Adenosine Diphosphate Mitochondrial ADP, ATP Translocases Binding Sites Mitochondria

Calcineurin inhibition enhances

Priyanka Das, Alejandro Aballay, Jogender Singh
1.00
Animals Caenorhabditis elegans Longevity Caenorhabditis elegans Proteins Calcineurin

Classifications MeSH