MRI characteristics of MOG-Ab associated disease in adults: An update.
Aquaporin-4
Imaging
Myelin Oligodendrocyte Glycoprotein
Myelitis
Neuromyelitis Optica
Optic neuritis
Journal
Revue neurologique
ISSN: 0035-3787
Titre abrégé: Rev Neurol (Paris)
Pays: France
ID NLM: 2984779R
Informations de publication
Date de publication:
Historique:
received:
12
05
2020
revised:
20
06
2020
accepted:
23
06
2020
pubmed:
14
10
2020
medline:
7
8
2021
entrez:
13
10
2020
Statut:
ppublish
Résumé
Our knowledge of the radiological spectrum of myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD) is growing rapidly. An update on the radiological features of the disease, and its evolution is thus necessary. Magnetic resonance imaging (MRI) has an increasingly important role in the differential diagnosis of MOGAD particularly from aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD), and multiple sclerosis (MS). Differentiating these conditions is of prime importance because the management is different between the three inflammatory diseases, and thus could prevent further attack-related disability. Therefore, identifying the MRI features suggestive of MOGAD has diagnostic and prognostic implications. We herein review optic nerve, spinal cord and the brain MRI findings from MOGAD adult patients, and compare them to AQP4-NMOSD and MS.
Identifiants
pubmed: 33046261
pii: S0035-3787(20)30679-2
doi: 10.1016/j.neurol.2020.06.016
pii:
doi:
Substances chimiques
Aquaporin 4
0
Autoantibodies
0
Myelin-Oligodendrocyte Glycoprotein
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
39-50Informations de copyright
Copyright © 2020 Elsevier Masson SAS. All rights reserved.