Direct visualization of the extracellular binding structure of E-cadherins in liquid.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
12 10 2020
12 10 2020
Historique:
received:
06
05
2020
accepted:
19
08
2020
entrez:
13
10
2020
pubmed:
14
10
2020
medline:
29
12
2020
Statut:
epublish
Résumé
E-cadherin is a key Ca-dependent cell adhesion molecule, which is expressed on many cell surfaces and involved in cell morphogenesis, embryonic development, EMT, etc. The fusion protein E-cad-Fc consists of the extracellular domain of E-cadherin and the IgG Fc domain. On plates coated with this chimeric protein, ES/iPS cells are cultivated particularly well and induced to differentiate. The cells adhere to the plate via E-cad-Fc in the presence of Ca
Identifiants
pubmed: 33046720
doi: 10.1038/s41598-020-72517-2
pii: 10.1038/s41598-020-72517-2
pmc: PMC7552386
doi:
Substances chimiques
Cadherins
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17044Références
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