Short-Term Follow-Up of Self-Isolated COVID-19 Patients with Smell and Taste Dysfunction in Greece: Two Phenotypes of Recovery.
COVID-19
Gustatory dysfunction
Olfactory dysfunction
Smell
Taste
Journal
ORL; journal for oto-rhino-laryngology and its related specialties
ISSN: 1423-0275
Titre abrégé: ORL J Otorhinolaryngol Relat Spec
Pays: Switzerland
ID NLM: 0334721
Informations de publication
Date de publication:
2020
2020
Historique:
received:
08
06
2020
accepted:
05
09
2020
pubmed:
14
10
2020
medline:
15
12
2020
entrez:
13
10
2020
Statut:
ppublish
Résumé
The course of anosmia and ageusia in COVID-19 patients is not yet clearly known. We present short-term follow-up data concerning mild to moderate disease in home-quarantined COVID-19 patients in Greece. We provided a symptom questionnaire and instructions for a self-administered home smell-and-taste test to 79 positive COVID-19 patients from 2 tertiary hospitals in Greece. The patients recorded their subjective symptoms before and during infection as well as 4 weeks after the diagnosis. The patients also underwent the home test during infection and 4 weeks later. Twenty-nine patients (36.7%) reported a loss of smell, and 21 (27.8%) reported a loss of taste, with equal prevalences between genders. We observed 2 types of recovery, i.e., a rapid, almost complete recovery, and a second slower and partial recovery. The type of recovery was not age related. A rapid recovery was observed in two thirds of the patients, with their olfactory ratings presenting a trend towards significance in correlation with nasal obstruction. A slow recovery in olfaction was correlated with low intensity ratings in odors with a trigeminal compound. The loss of taste was more pronounced in sweet and salty intensity ratings. Chemosensory deficits associated with COVID-19 infection were quite frequent among the Greek patients with mild or moderate disease who, in most cases, returned to normal within 4 weeks. However, 1 in 3 patients presented with persistent olfactory and gustatory dysfunction in the short term.
Identifiants
pubmed: 33049753
pii: 000511436
doi: 10.1159/000511436
pmc: PMC7649691
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
295-303Informations de copyright
© 2020 S. Karger AG, Basel.
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