Predictors of outcomes in patients with mitral regurgitation undergoing percutaneous valve repair.
Aged
Cardiac Catheterization
/ methods
Cardiac Surgical Procedures
/ methods
Echocardiography
/ methods
Female
Heart Failure
/ physiopathology
Heart Valve Prosthesis Implantation
/ methods
Hospitalization
Humans
Kaplan-Meier Estimate
Male
Mitral Valve
/ physiopathology
Mitral Valve Insufficiency
/ physiopathology
Retrospective Studies
Treatment Outcome
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
13 10 2020
13 10 2020
Historique:
received:
26
05
2020
accepted:
24
09
2020
entrez:
14
10
2020
pubmed:
15
10
2020
medline:
14
1
2021
Statut:
epublish
Résumé
Percutaneous mitral valve repair has been increasingly performed worldwide after approval. We sought to investigate predictors of clinical outcome in patients with mitral regurgitation undergoing percutaneous valve repair. The MITRA-UMG study, a single-centre registry, retrospectively collected consecutive patients with symptomatic moderate-to-severe or severe MR undergoing MitraClip therapy. The primary endpoint was the composite of cardiovascular death or rehospitalization for heart failure. Between March 2012 and July 2018, a total of 150 consecutive patients admitted to our institution were included. Procedural success was obtained in 95.3% of patients. The composite primary endpoint of cardiovascular death or rehospitalization for HF was met in 55 patients (37.9%) with cumulative incidences of 7.6%, 26.2%, at 30 days and 1-year, respectively. In the Cox multivariate model, NYHA functional class and left ventricular end-diastolic volume index (LVEDVi), independently increased the risk of the primary endpoint at long-term follow-up. At Kaplan-Meier analysis, a LVEDVi > 92 ml/m
Identifiants
pubmed: 33051585
doi: 10.1038/s41598-020-74407-z
pii: 10.1038/s41598-020-74407-z
pmc: PMC7555528
doi:
Types de publication
Journal Article
Observational Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
17144Références
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