Phidianidine A and Synthetic Analogues as Naturally Inspired Marine Antifoulants.

Animals Ascomycota / drug effects Biofouling Indole Alkaloids / chemistry Oxadiazoles / chemistry Seawater Thoracica

Journal

Journal of natural products
ISSN: 1520-6025
Titre abrégé: J Nat Prod
Pays: United States
ID NLM: 7906882

Informations de publication

Date de publication:
25 11 2020
Historique:
pubmed: 16 10 2020
medline: 28 10 2021
entrez: 15 10 2020
Statut: ppublish

Résumé

Stationary and slow-moving marine organisms regularly employ a natural product chemical defense to prevent being colonized by marine micro- and macroorganisms. While these natural antifoulants can be structurally diverse, they often display highly conserved chemistries and physicochemical properties, suggesting a natural marine antifouling pharmacophore. In our current report, we investigate the marine natural product phidianidine A, which displays several chemical properties found in highly potent marine antifoulants. Phidianidine A and synthetic analogues were screened against the settlement and metamorphosis of

Identifiants

DOI: 10.1021/acs.jnatprod.0c00881 PMID: 33054188
pubmed: 33054188
doi: 10.1021/acs.jnatprod.0c00881
doi:

Substances chimiques

Indole Alkaloids 0
Oxadiazoles 0
phidianidine A 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3413-3423

Auteurs

Christophe Labriere (C)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.

Vijayaragavan Elumalai (V)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.

Jannie Staffansson (J)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.

Gunnar Cervin (G)

Department of Marine Sciences, Tjärnö Marine Laboratory, University of Gothenburg, SE-452 96 Strömstad, Sweden.

Tiffany Le Norcy (T)

Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, F-56100 Lorient, France.

Hugo Denardou (H)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.

Karine Réhel (K)

Univ. Bretagne-Sud, EA 3884, LBCM, IUEM, F-56100 Lorient, France.

Lindon W K Moodie (LWK)

Department of Medicinal Chemistry and Uppsala Antibiotic Centre, Biomedical Centre, Uppsala University, 75123 Uppsala, Sweden.
ORCID: 0000-0002-9500-4535

Claire Hellio (C)

Univ. Brest, Laboratoire des Sciences de l'Environnement MARin (LEMAR), CNRS, IRD, IFREMER, Brest 29285, France.

Henrik Pavia (H)

Department of Marine Sciences, Tjärnö Marine Laboratory, University of Gothenburg, SE-452 96 Strömstad, Sweden.

Jørn H Hansen (JH)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.
ORCID: 0000-0002-3888-5217

Johan Svenson (J)

Department of Chemistry, Chemical Synthesis and Analysis Group, UiT The Arctic University of Norway, N-9037 Tromsø, Norway.
Department of Chemistry, Biomaterial & Textile, RISE Research Institutes of Sweden, Box 857, 501 15 Borås, Sweden.
ORCID: 0000-0002-4729-9359

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Contamination de matériel › Encrassement biologique › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Indolizine › Indolizidines › Alcaloïdes indoliques › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Oxazoles › Oxadiazoles › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Phénomènes biologiques › Phénomènes écologiques et environnementaux › Eaux salées › Eau de mer › Phidianidine A and Synthetic Analogues as...
questionsmedicales.fr › Eucaryotes › Animaux › Invertébrés › Arthropodes › Crustacea › Thoracica › Phidianidine A and Synthetic Analogues as...