Contrasting Associations Between Diabetes and Cardiovascular Mortality Rates in Low-, Middle-, and High-Income Countries: Cohort Study Data From 143,567 Individuals in 21 Countries in the PURE Study.
Adult
Aged
Cardiovascular Diseases
/ mortality
Cohort Studies
Developed Countries
/ statistics & numerical data
Developing Countries
/ statistics & numerical data
Diabetes Mellitus
/ epidemiology
Female
Humans
Income
/ statistics & numerical data
Male
Middle Aged
Mortality
Poverty
/ statistics & numerical data
Prospective Studies
Risk Factors
Rural Population
/ statistics & numerical data
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
12 2020
12 2020
Historique:
received:
20
04
2020
accepted:
18
09
2020
pubmed:
17
10
2020
medline:
29
5
2021
entrez:
16
10
2020
Statut:
ppublish
Résumé
We aimed to compare cardiovascular (CV) events, all-cause mortality, and CV mortality rates among adults with and without diabetes in countries with differing levels of income. The Prospective Urban Rural Epidemiology (PURE) study enrolled 143,567 adults aged 35-70 years from 4 high-income countries (HIC), 12 middle-income countries (MIC), and 5 low-income countries (LIC). The mean follow-up was 9.0 ± 3.0 years. Among those with diabetes, CVD rates (LIC 10.3, MIC 9.2, HIC 8.3 per 1,000 person-years, CVD rates, all-cause mortality, and CV mortality were markedly higher among those with diabetes in LIC compared with MIC and HIC with mortality risk remaining unchanged even after adjustment for risk factors and treatments. There is an urgent need to improve access to care to those with diabetes in LIC to reduce the excess mortality rates, particularly among those in the poorer strata of society.
Identifiants
pubmed: 33060076
pii: dc20-0886
doi: 10.2337/dc20-0886
pmc: PMC7770267
doi:
Banques de données
figshare
['10.2337/figshare.12985481']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
3094-3101Informations de copyright
© 2020 by the American Diabetes Association.
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