SUSA2 is an F-box protein required for autoimmunity mediated by paired NLRs SOC3-CHS1 and SOC3-TN2.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
15 10 2020
15 10 2020
Historique:
received:
20
09
2019
accepted:
24
09
2020
entrez:
16
10
2020
pubmed:
17
10
2020
medline:
3
11
2020
Statut:
epublish
Résumé
Both higher plants and mammals rely on nucleotide-binding leucine-rich repeat (NLR) immune receptors to detect pathogens and initiate immunity. Upon effector recognition, plant NLRs oligomerize for defense activation, the mechanism of which is poorly understood. We previously showed that disruption of the E3 ligase, Senescence-Associated E3 Ubiquitin Ligase 1 (SAUL1) leads to the activation of the NLR SOC3. Here, we report the identification of suppressor of saul1 2 (susa2) and susa3 from the saul1-1 suppressor screen. Pairwise interaction analysis suggests that both SUSA proteins interact with components of an SCF
Identifiants
pubmed: 33060601
doi: 10.1038/s41467-020-19033-z
pii: 10.1038/s41467-020-19033-z
pmc: PMC7562919
doi:
Substances chimiques
ASK1 protein, Arabidopsis
0
Arabidopsis Proteins
0
CHS1 protein, Arabidopsis
0
F-Box Proteins
0
NLR Proteins
0
Receptors, Immunologic
0
SOC3 protein, Arabidopsis
0
SAUL1 protein, Arabidopsis
EC 2.3.2.27
Ubiquitin-Protein Ligases
EC 2.3.2.27
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
5190Références
Plant Physiol. 2018 Nov;178(3):1284-1295
pubmed: 30185442
EMBO J. 2014 Sep 1;33(17):1941-59
pubmed: 25024433
Nat Commun. 2016 Jan 05;7:10269
pubmed: 26728313
Science. 2014 Apr 18;344(6181):299-303
pubmed: 24744375
PLoS Genet. 2016 Sep 12;12(9):e1006301
pubmed: 27618443
Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11777-82
pubmed: 14504384
Mol Cell. 2002 Aug;10(2):417-26
pubmed: 12191486
Plant Cell. 2007 Nov;19(11):3791-804
pubmed: 18032631
Elife. 2019 Apr 05;8:
pubmed: 30950791
Nat Genet. 2019 Oct;51(10):1540-1548
pubmed: 31570888
EMBO J. 2003 Nov 3;22(21):5679-89
pubmed: 14592967
Science. 2013 Aug 16;341(6147):746-51
pubmed: 23950531
New Phytol. 2014 Jun;202(4):1320-34
pubmed: 24611624
Annu Rev Plant Biol. 2015;66:487-511
pubmed: 25494461
Cell. 2015 May 21;161(5):1074-1088
pubmed: 26000483
Nat Immunol. 2011 Aug 18;12(9):817-26
pubmed: 21852785
Science. 2002 Mar 15;295(5562):2073-6
pubmed: 11847307
Science. 2009 May 8;324(5928):742-4
pubmed: 19423812
Mol Plant. 2014 Dec;7(12):1801-4
pubmed: 25237053
Annu Rev Plant Biol. 2009;60:139-64
pubmed: 19014346
Science. 2019 Apr 5;364(6435):
pubmed: 30948527
Histochem Cell Biol. 2016 Apr;145(4):373-88
pubmed: 26847179
Science. 2019 Aug 23;365(6455):793-799
pubmed: 31439792
Front Plant Sci. 2011 Oct 31;2:71
pubmed: 22639607
Plant Cell. 2003 Nov;15(11):2636-46
pubmed: 14576290
Plant J. 2014 Aug;79(3):427-39
pubmed: 24889324
Plant Cell. 2010 Sep;22(9):3153-63
pubmed: 20841424
Cell. 2015 May 21;161(5):1089-1100
pubmed: 26000484
Science. 2019 Apr 5;364(6435):
pubmed: 30948526
Science. 2019 Aug 23;365(6455):799-803
pubmed: 31439793
New Phytol. 2019 Mar;221(4):2054-2066
pubmed: 30317650
Plant Cell. 2015 Jan;27(1):9-19
pubmed: 25604443
Nat Plants. 2015;1:
pubmed: 27054042
PLoS Genet. 2016 Apr 15;12(4):e1005990
pubmed: 27082651
Trends Plant Sci. 2019 Aug;24(8):688-699
pubmed: 31266697
Sci Rep. 2015 Mar 05;5:8792
pubmed: 25740259
Trends Biochem Sci. 2010 Apr;35(4):199-207
pubmed: 20096590
Mol Cell. 1999 Jul;4(1):21-33
pubmed: 10445024
New Phytol. 2019 Apr;222(2):938-953
pubmed: 30585636
Plant Physiol. 2008 Feb;146(2):368-76
pubmed: 18065554
Plant J. 2009 Oct;60(2):218-26
pubmed: 19519800
Science. 2016 Dec 2;354(6316):
pubmed: 27934708
Nat Commun. 2019 Jul 19;10(1):3252
pubmed: 31324801
Plant Physiol. 2002 Mar;128(3):997-1007
pubmed: 11891255
Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8585-90
pubmed: 12084919
Nature. 1998 Dec 10;396(6711):590-4
pubmed: 9859996
Cell Host Microbe. 2012 Mar 15;11(3):253-63
pubmed: 22423965
Plant Cell. 2005 Apr;17(4):1306-16
pubmed: 15772285
Plant J. 2010 Mar;61(6):1053-66
pubmed: 20409278
Plant J. 2009 Jul;59(1):39-51
pubmed: 19309463
Plant Sci. 2019 Jul;284:127-134
pubmed: 31084865
Plant Cell. 1998 Jul;10(7):1151-61
pubmed: 9668134
Mol Plant Microbe Interact. 2001 Oct;14(10):1131-9
pubmed: 11605952
Plant Cell. 2008 Mar;20(3):697-719
pubmed: 18375657
Mol Plant Microbe Interact. 2010 Dec;23(12):1531-6
pubmed: 20653410
Trends Plant Sci. 2004 Apr;9(4):196-202
pubmed: 15063870
New Phytol. 2017 Feb;213(3):1330-1345
pubmed: 27699788
New Phytol. 2017 Sep;215(4):1516-1532
pubmed: 28691210
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10306-11
pubmed: 9707643
J Biol Chem. 2004 Apr 16;279(16):16511-7
pubmed: 14761955
Plant Cell. 2013 Apr;25(4):1463-81
pubmed: 23548743
Cell Host Microbe. 2015 Sep 9;18(3):285-95
pubmed: 26355215
J Biosci. 2006 Mar;31(1):137-55
pubmed: 16595883
Physiol Plant. 2016 Oct;158(2):180-99
pubmed: 26910207
Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9556-63
pubmed: 19487680
Trends Immunol. 2014 Nov;35(11):562-70
pubmed: 25308923
Plant Cell. 2015 Mar;27(3):857-73
pubmed: 25747881
Plant Physiol. 2012 Aug;159(4):1477-87
pubmed: 22706448
Mol Plant Microbe Interact. 2016 Jan;29(1):69-80
pubmed: 26505534
Plant J. 2013 Aug;75(4):553-65
pubmed: 23651299
Plant Physiol. 2012 Sep;160(1):15-27
pubmed: 22689893