Multiplying the efficiency and impact of biofortification through metabolic engineering.


Journal

Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555

Informations de publication

Date de publication:
15 10 2020
Historique:
received: 25 06 2020
accepted: 24 09 2020
entrez: 16 10 2020
pubmed: 17 10 2020
medline: 3 11 2020
Statut: epublish

Résumé

Ending all forms of hunger by 2030, as set forward in the UN-Sustainable Development Goal 2 (UN-SDG2), is a daunting but essential task, given the limited timeline ahead and the negative global health and socio-economic impact of hunger. Malnutrition or hidden hunger due to micronutrient deficiencies affects about one third of the world population and severely jeopardizes economic development. Staple crop biofortification through gene stacking, using a rational combination of conventional breeding and metabolic engineering strategies, should enable a leap forward within the coming decade. A number of specific actions and policy interventions are proposed to reach this goal.

Identifiants

pubmed: 33060603
doi: 10.1038/s41467-020-19020-4
pii: 10.1038/s41467-020-19020-4
pmc: PMC7567076
doi:

Substances chimiques

Micronutrients 0
Minerals 0
Provitamins 0
Vitamins 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

5203

Références

J Nutr. 2016 Dec;146(12):2551-2558
pubmed: 27798345
Glob Food Sec. 2017 Sep;14:23-30
pubmed: 28989861
GM Crops Food. 2017 Jul 3;8(3):149-155
pubmed: 28362553
Annu Rev Nutr. 2017 Aug 21;37:447-476
pubmed: 28564554
Curr Opin Biotechnol. 2017 Apr;44:202-211
pubmed: 28329726
PLoS One. 2015 Dec 16;10(12):e0143497
pubmed: 26673631
Mol Plant. 2012 Mar;5(2):339-52
pubmed: 22155949
Adv Nutr. 2014 Sep;5(5):568-70
pubmed: 25469399
Science. 2000 Jan 14;287(5451):303-5
pubmed: 10634784
Front Nutr. 2018 Feb 14;5:12
pubmed: 29492405
Plant Cell. 2012 Feb;24(2):395-414
pubmed: 22374394
Plant Biotechnol J. 2019 Jan;17(1):9-20
pubmed: 29734523
Nat Biotechnol. 2012 Dec;30(12):1170-2
pubmed: 23222780
Prog Cardiovasc Dis. 2020 Jul 10;:
pubmed: 32653438
Plant Mol Biol. 2019 Mar;99(4-5):317-328
pubmed: 30645710
Plant Physiol. 2013 Jul;162(3):1618-31
pubmed: 23669743
Lancet. 2016 Oct 8;388(10053):1545-1602
pubmed: 27733282
Nat Commun. 2020 Mar 4;11(1):1178
pubmed: 32132530
Plant Biotechnol J. 2009 Sep;7(7):631-44
pubmed: 19702755
Mol Plant. 2018 Jan 8;11(1):175-188
pubmed: 29277427
Indian J Community Health. 2014 Nov;26(Suppl 1):3-5
pubmed: 26120254
Curr Opin Biotechnol. 2017 Apr;44:161-168
pubmed: 28231514
Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):11040-5
pubmed: 27621466
Lancet. 2013 Aug 3;382(9890):427-451
pubmed: 23746772
Nat Plants. 2019 Jun;5(6):563-567
pubmed: 31160704
Sci Rep. 2017 Jul 31;7(1):6883
pubmed: 28761150
Sci Rep. 2016 Jan 25;6:19792
pubmed: 26806528
Science. 2019 Mar 29;363(6434):1390-1391
pubmed: 30923209
Planta. 2015 Jul;242(1):353-63
pubmed: 25963517
Plant Biotechnol J. 2018 Jun;16(6):1186-1200
pubmed: 29193665
Plant J. 2019 Sep;99(6):1047-1065
pubmed: 31063672
Plant Mol Biol. 2019 Nov;101(4-5):415-437
pubmed: 31542868
Nat Rev Endocrinol. 2016 May;12(5):274-89
pubmed: 27032981
Food Chem. 2019 Apr 25;278:773-779
pubmed: 30583442
Nat Biotechnol. 2007 Nov;25(11):1277-9
pubmed: 17934451
New Phytol. 2009;182(1):49-84
pubmed: 19192191
Ann Nutr Metab. 2015;66 Suppl 2:22-33
pubmed: 26045325
J Agric Food Chem. 2015 Oct 21;63(41):9083-92
pubmed: 26424551
Glob Food Sec. 2017 Mar;12:49-58
pubmed: 28580239
Nat Biotechnol. 2015 Oct;33(10):1029-32
pubmed: 26448082
J Agric Food Chem. 2019 Jul 17;67(28):7986-7994
pubmed: 31282158
PLoS One. 2017 Apr 11;12(4):e0175554
pubmed: 28399168
Nat Biotechnol. 2015 Oct;33(10):1076-8
pubmed: 26389575
J Agric Food Chem. 2014 Jul 9;62(27):6317-25
pubmed: 24930501
Plant Biotechnol J. 2016 Jan;14(1):195-205
pubmed: 25857664
Nat Biotechnol. 2005 Apr;23(4):482-7
pubmed: 15793573
N Biotechnol. 2012 Feb 15;29(3):432-42
pubmed: 22154941
J Exp Bot. 2019 Mar 11;70(5):1539-1551
pubmed: 30753561
Glob Health Action. 2019;12(1):1588513
pubmed: 31062664
Nutr J. 2018 Sep 15;17(1):86
pubmed: 30219062
Cochrane Database Syst Rev. 2017 Mar 11;3:CD008524
pubmed: 28282701

Auteurs

Dominique Van Der Straeten (D)

Laboratory of Functional Plant Biology, Department of Biology, Ghent University, K.L. Ledeganckstraat 35, B-9000, Ghent, Belgium. Dominique.VanDerStraeten@UGent.be.

Navreet K Bhullar (NK)

Department of Biology, Institute of Molecular Plant Biology, ETH Zurich, Universitaetstrasse 2, 8092, Zurich, Switzerland.

Hans De Steur (H)

Department of Agricultural Economics, Ghent University, Coupure Links 653, B-9000, Ghent, Belgium.

Wilhelm Gruissem (W)

Department of Biology, Institute of Molecular Plant Biology, ETH Zurich, Universitaetstrasse 2, 8092, Zurich, Switzerland.
Advanced Plant Biotechnology Center, National Chung Hsing University, Taichung, Taiwan.

Donald MacKenzie (D)

Donald Danforth Plant Science Center, St. Louis, MO, 63132, USA.

Wolfgang Pfeiffer (W)

HarvestPlus c/o IFPRI, Washington, DC, USA.

Matin Qaim (M)

Department of Agricultural Economics and Rural Development, University of Goettingen, Platz der Goettinger Sieben 5, 37073, Goettingen, Germany.

Inez Slamet-Loedin (I)

International Rice Research Institute, Manila, The Philippines.

Simon Strobbe (S)

Laboratory of Functional Plant Biology, Department of Biology, Ghent University, K.L. Ledeganckstraat 35, B-9000, Ghent, Belgium.

Joe Tohme (J)

International Center for Tropical Agriculture, CIAT, Cali, Colombia.

Kurniawan Rudi Trijatmiko (KR)

International Rice Research Institute, Manila, The Philippines.

Hervé Vanderschuren (H)

Tropical Crop Improvement Lab, Department of Biosystems, KU Leuven, Heverlee, Belgium.
Plant Genetics, TERRA Teaching and Research Center, Gembloux Agro-Biotech, University of Liège, Gembloux, Belgium.

Marc Van Montagu (M)

International Plant Biotechnology Outreach, B-9052, Zwijnaarde, Belgium.

Chunyi Zhang (C)

Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.

Howarth Bouis (H)

International Food Policy Research Institute, Washington, DC, USA. H.Bouis@CGIAR.org.

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Classifications MeSH