Epinephrine soaked tampons induced transient acute dilated cardiomyopathy during FESS procedure.


Journal

BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539

Informations de publication

Date de publication:
16 10 2020
Historique:
received: 05 06 2020
accepted: 16 09 2020
entrez: 17 10 2020
pubmed: 18 10 2020
medline: 2 2 2021
Statut: epublish

Résumé

Epinephrine, in all modes of use, may pose a wide range of cardiotoxic events, ranging from sinus tachycardia to heart failure, life threatening arrhythmias, and even death. Because of daily and extensive use of epinephrine, these unusual and rare events tend to be forgotten by physicians. We present a case of dilated cardiomyopathy that developed following routine use of epinephrine-impregnated tampons during function endoscopic sinus (FESS) surgery. A healthy, 24-year-old man with no family history of heart disease has undergone elective surgery under general anesthesia to repair the paranasal sinuses using endoscopic approach. During surgery, soon after being treated with 1: 1000 diluted epinephrine-soaked tampons, an hypertensive crisis was noticed followed by pulseless electrical activity. An extensive examination led to the diagnosis of non-ischemic dilated cardiomyopathy. After several days of heart failure medical therapy, complete resolution of all structural and functional changes was achieved. In our case, we present an unusual and rare event of acute dilated cardiomyopathy following the use of epinephrine-soaked tampons during elective FESS surgery. A prompt response was observed after several days of heart failure treatment. Awareness of the epinephrine cardiotoxic potential even in the form of soaked tampons is essential for proper diagnosis and prompt treatment.

Sections du résumé

BACKGROUND
Epinephrine, in all modes of use, may pose a wide range of cardiotoxic events, ranging from sinus tachycardia to heart failure, life threatening arrhythmias, and even death. Because of daily and extensive use of epinephrine, these unusual and rare events tend to be forgotten by physicians. We present a case of dilated cardiomyopathy that developed following routine use of epinephrine-impregnated tampons during function endoscopic sinus (FESS) surgery.
CASE PRESENTATION
A healthy, 24-year-old man with no family history of heart disease has undergone elective surgery under general anesthesia to repair the paranasal sinuses using endoscopic approach. During surgery, soon after being treated with 1: 1000 diluted epinephrine-soaked tampons, an hypertensive crisis was noticed followed by pulseless electrical activity. An extensive examination led to the diagnosis of non-ischemic dilated cardiomyopathy. After several days of heart failure medical therapy, complete resolution of all structural and functional changes was achieved.
CONCLUSION
In our case, we present an unusual and rare event of acute dilated cardiomyopathy following the use of epinephrine-soaked tampons during elective FESS surgery. A prompt response was observed after several days of heart failure treatment. Awareness of the epinephrine cardiotoxic potential even in the form of soaked tampons is essential for proper diagnosis and prompt treatment.

Identifiants

pubmed: 33066731
doi: 10.1186/s12872-020-01706-8
pii: 10.1186/s12872-020-01706-8
pmc: PMC7566064
doi:

Substances chimiques

Adrenergic Agonists 0
Epinephrine YKH834O4BH

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

452

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Auteurs

Sari Naddaf (S)

Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Scott Ehrenberg (S)

Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.

Rony Hakim (R)

Department of Anaesthesia, Emek Medical Center, Afula, Israel.

Muhamad Mahamid (M)

Heart Institute, Emek Medical Center, Afula, Israel.

Yoav Turgeman (Y)

Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Heart Institute, Emek Medical Center, Afula, Israel.

Ofir Koren (O)

Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel. Drkorenofir@gmail.com.
Heart Institute, Emek Medical Center, Afula, Israel. Drkorenofir@gmail.com.

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Classifications MeSH