Molecular Epidemiology of Giardia Infections in the Genomic Era.
Giardia
genomics
genotyping
molecular epidemiology
population genetics
public health
Journal
Trends in parasitology
ISSN: 1471-5007
Titre abrégé: Trends Parasitol
Pays: England
ID NLM: 100966034
Informations de publication
Date de publication:
02 2021
02 2021
Historique:
received:
23
06
2020
revised:
22
09
2020
accepted:
22
09
2020
pubmed:
18
10
2020
medline:
3
3
2021
entrez:
17
10
2020
Statut:
ppublish
Résumé
Giardia duodenalis is a major gastrointestinal parasite of humans and animals across the globe. It is also of interest from an evolutionary perspective as it possesses many features that are unique among the eukaryotes, including its distinctive binucleate cell structure. While genomic analysis of a small number of isolates has provided valuable insights, efforts to understand the epidemiology of the disease and the population biology of the parasite have been limited by the molecular tools currently available. We review these tools and assess the impact of affordable and rapid genome sequencing systems increasingly being deployed in diagnostic settings. While these technologies have direct implications for public and veterinary health, they will also improve our understanding of the unique biology of this fascinating parasite.
Identifiants
pubmed: 33067130
pii: S1471-4922(20)30256-7
doi: 10.1016/j.pt.2020.09.013
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
142-153Subventions
Organisme : Chief Scientist Office
ID : TCS/18/22
Pays : United Kingdom
Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.