Choosing the right drug: status and future of endocannabinoid research for the prevention of drug-seeking reinstatement.

Endocannabinoids Humans Ligands Pharmaceutical Preparations Reward Substance-Related Disorders / drug therapy

Journal

Current opinion in pharmacology
ISSN: 1471-4973
Titre abrégé: Curr Opin Pharmacol
Pays: England
ID NLM: 100966133

Informations de publication

Date de publication:
02 2021
Historique:
received: 06 06 2020
revised: 06 08 2020
accepted: 25 08 2020
pubmed: 18 10 2020
medline: 26 10 2021
entrez: 17 10 2020
Statut: ppublish

Résumé

Prolonged exposure to drugs of abuse leads to severe alterations in mesocorticolimbic dopamine circuitry deeply implicated in substance use disorders. Despite considerable efforts, few medications to reduce relapse rates are currently available. To solve this issue, researchers are uncovering therapeutic opportunities offered by the endocannabinoid system. The cannabinoid receptor type 1 (CB

Identifiants

DOI: 10.1016/j.coph.2020.08.014 PMID: 33068883
pubmed: 33068883
pii: S1471-4892(20)30065-5
doi: 10.1016/j.coph.2020.08.014
pii:
doi:

Substances chimiques

Endocannabinoids 0
Ligands 0
Pharmaceutical Preparations 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

29-38

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Miguel Á Luján (MÁ)

Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.

Joseph F Cheer (JF)

Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, USA.

Miriam Melis (M)

Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria, Monserrato, Italy. Electronic address: myriam@unica.it.

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Classifications MeSH

questionsmedicales.fr › Lipides › Acides gras › Endocannabinoïdes › Choosing the right drug: status and future of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Choosing the right drug: status and future of...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Ligands › Choosing the right drug: status and future of...
questionsmedicales.fr › Préparations pharmaceutiques › Choosing the right drug: status and future of...
questionsmedicales.fr › Phénomènes psychologiques › Processus mentaux › Renforcement (psychologie) › Récompense › Choosing the right drug: status and future of...
questionsmedicales.fr › Troubles mentaux › Troubles liés à une substance › Choosing the right drug: status and future of...