Torsade de pointes induced by intravenous amiodarone therapy accompanied by marked augmentation of the transmural dispersion of repolarization in a patient with tachycardia-induced-cardiomyopathy.
Tpeak-Tend interval
amiodarone
hemodialysis
tachycardia-induced-cardiomyopathy
torsade de pointes
transmural dispersion of repolarization
Journal
Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
ISSN: 1542-474X
Titre abrégé: Ann Noninvasive Electrocardiol
Pays: United States
ID NLM: 9607443
Informations de publication
Date de publication:
05 2021
05 2021
Historique:
revised:
13
09
2020
received:
15
08
2020
accepted:
26
09
2020
pubmed:
19
10
2020
medline:
15
12
2021
entrez:
18
10
2020
Statut:
ppublish
Résumé
We report a 77-year-old human on renal dialysis for end-stage renal disease with heart failure and atrial fibrillation (AF) complicated by a high ventricular frequency. The underlying disease was thought as tachycardia-induced-cardiomyopathy. Intravenous infusion of amiodarone was initiated, and direct current cardioversion succeeded in converting AF to sinus rhythm. Then, excessive increases in the QT and Tpeak-Tend (Tp-e) intervals were seen and hypokalemia induced by hemodialysis led to the development of numerous episodes of torsades de pointes (TdP). Magnesium repletion was effective in preventing TdP, while Tp-e intervals returned to the previous values 2 days after the discontinuation of amiodarone.
Identifiants
pubmed: 33070441
doi: 10.1111/anec.12810
pmc: PMC8164138
doi:
Substances chimiques
Anti-Arrhythmia Agents
0
Amiodarone
N3RQ532IUT
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
e12810Informations de copyright
© 2020 The Authors. Annals of Noninvasive Electrocardiology published by Wiley Periodicals LLC.
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