Death Rate Due to COVID-19 in Alzheimer's Disease and Frontotemporal Dementia.


Journal

Journal of Alzheimer's disease : JAD
ISSN: 1875-8908
Titre abrégé: J Alzheimers Dis
Pays: Netherlands
ID NLM: 9814863

Informations de publication

Date de publication:
2020
Historique:
pubmed: 20 10 2020
medline: 26 11 2020
entrez: 19 10 2020
Statut: ppublish

Résumé

We aimed to evaluate the frequency and mortality of COVID-19 in patients with Alzheimer's disease (AD) and frontotemporal dementia (FTD). We conducted an observational case series. We enrolled 204 patients, 15.2% of whom were diagnosed with COVID-19, and 41.9% of patients with the infection died. Patients with AD were older than patients with FTD (80.36±8.77 versus 72.00±8.35 years old) and had a higher prevalence of arterial hypertension (55.8% versus 26.3%). COVID-19 occurred in 7.3% of patients living at home, but 72.0% of those living at care homes. Living in care facilities and diagnosis of AD were independently associated with a higher probability of death. We found that living in care homes is the most relevant factor for an increased risk of COVID-19 infection and death, with AD patients exhibiting a higher risk than those with FTD.

Identifiants

pubmed: 33074240
pii: JAD200940
doi: 10.3233/JAD-200940
doi:

Types de publication

Letter Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

537-541

Auteurs

Jordi A Matias-Guiu (JA)

Department of Neurology, Institute of Neurosciences, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Universidad Complutense de Madrid, Madrid, Spain.

Vanesa Pytel (V)

Department of Neurology, Institute of Neurosciences, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Universidad Complutense de Madrid, Madrid, Spain.

Jorge Matías-Guiu (J)

Department of Neurology, Institute of Neurosciences, Hospital Clínico San Carlos, San Carlos Health Research Institute (IdISSC), Universidad Complutense de Madrid, Madrid, Spain.

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Classifications MeSH