Suspected COVID-19-related reticulated purpura of the soles in an infant.

COVID-19 SARS-CoV-2 acro-ischemic lesions chilblain exanthem immunohistochemistry pernio skin viral diseases

Journal

Pediatric dermatology
ISSN: 1525-1470
Titre abrégé: Pediatr Dermatol
Pays: United States
ID NLM: 8406799

Informations de publication

Date de publication:
Jan 2021
Historique:
pubmed: 22 10 2020
medline: 5 3 2021
entrez: 21 10 2020
Statut: ppublish

Résumé

A growing number of skin lesions during the COVID-19 pandemic are being recognized. Acral ischemic lesions identical to chilblains are most typical in children and young adults. We report an infant girl, aged 1 month and 29 days, with a peculiar reticulated purpuric eruption on her soles, with positive immunohistochemistry for SARS-CoV-2 in the endothelia of dermal blood vessels. The patient had an excellent outcome without specific therapy.

Identifiants

pubmed: 33085141
doi: 10.1111/pde.14409
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

301-303

Informations de copyright

© 2020 Wiley Periodicals LLC.

Références

Andina D, Noguera-Morel L, Bascuas-Arribas M, et al. Chilblains in children in the setting of COVID-19 pandemic. Pediatr Dermatol. 2020;37(3):406-411.
Torrelo A, Andina D, Santonja C, et al. Erythema multiforme-like lesions in children and COVID-19. Pediatr Dermatol. 2020;37(3):442-446.
Colmenero I, Colmenero I, Santonja C, et al. SARS-CoV-2 endothelial infection causes COVID-19 chilblains: histopathological, immunohistochemical and ultraestructural study of 7 paediatric cases. Br J Dermatol. 2020. https://doi.org/10.1111/bjd.19327. [Epub ahead of print].
Bosch-Amate X, Giavedoni P, Podlipnik S, et al. Retiform purpura as a dermatological sign of covid-19 coagulopathy. J Eur Acad Dermatol Venereol. 2020. https://doi.org/10.1111/jdv.16689. [Epub ahead of print].
Manalo IF, Smith MK, Cheeley J, Jacobs R. A dermatologic manifestation of COVID-19: transient livedo reticularis. J Am Acad Dermatol. 2020;83(2):700.
Varga Z, Flammer AJ, Steiger P, et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet. 2020;395(10234):1417-1418.
Magro C, Mulvey JJ, Berlin D, et al. Complement associated microvascular injury and thrombosis in the pathogenesis of severe COVID-19 infection: a report of five cases. Transl Res. 2020;220:1-13.

Auteurs

David Andina (D)

Emergency Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Isabel Colmenero (I)

Department of Pathology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Carlos Santonja (C)

Department of Pathology, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain.

Irene Muñoz de León (I)

Emergency Department, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Lucero Noguera-Morel (L)

Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Angela Hernández-Martín (A)

Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

Antonio Torrelo (A)

Department of Dermatology, Hospital Infantil Universitario Niño Jesús, Madrid, Spain.

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