Epithelial WNT2B and Desert Hedgehog Are Necessary for Human Colonoid Regeneration after Bacterial Cytotoxin Injury.
Bacteriology
Bioengineering
Cell Biology
Tissue Engineering
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
23 Oct 2020
23 Oct 2020
Historique:
received:
31
01
2020
revised:
03
06
2020
accepted:
24
09
2020
entrez:
22
10
2020
pubmed:
23
10
2020
medline:
23
10
2020
Statut:
epublish
Résumé
Intestinal regeneration and crypt hyperplasia after radiation or pathogen injury relies on Wnt signaling to stimulate stem cell proliferation. Mesenchymal Wnts are essential for homeostasis and regeneration in mice, but the role of epithelial Wnts remains largely uncharacterized. Using the enterohemorrhagic
Identifiants
pubmed: 33089106
doi: 10.1016/j.isci.2020.101618
pii: S2589-0042(20)30810-5
pmc: PMC7559866
doi:
Types de publication
Journal Article
Langues
eng
Pagination
101618Subventions
Organisme : NIDDK NIH HHS
ID : K01 DK106323
Pays : United States
Organisme : NIDDK NIH HHS
ID : U24 DK085532
Pays : United States
Organisme : NIAID NIH HHS
ID : P01 AI125181
Pays : United States
Organisme : NIDDK NIH HHS
ID : U01 DK103168
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK056338
Pays : United States
Informations de copyright
© 2020 The Author(s).
Déclaration de conflit d'intérêts
All authors have declared no conflict of interest.
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