Detrimental effect on the gut microbiota of 1,2-dicarbonyl compounds after in vitro gastro-intestinal and fermentative digestion.

Aldehydes / chemistry Digestion Fermentation Gastrointestinal Microbiome / drug effects Humans Intestinal Mucosa / metabolism Stomach / microbiology
3-Deoxyglucosone Antimicrobials Glyoxal Gut microbiota Methylglyoxal Short-chain-fatty-acids

Journal

Food chemistry
ISSN: 1873-7072
Titre abrégé: Food Chem
Pays: England
ID NLM: 7702639

Informations de publication

Date de publication:
30 Mar 2021
Historique:
received: 04 06 2020
revised: 25 09 2020
accepted: 25 09 2020
pubmed: 23 10 2020
medline: 31 12 2020
entrez: 22 10 2020
Statut: ppublish

Résumé

This study investigated the stability of dicarbonyl compounds (DCs), 3-deoxyglucosone (3-DG), glyoxal (GO) and methylglyoxal (MGO) during simulated gastrointestinal digestion processes and the impact these compounds have on the gut microbiota. DCs pass almost unaltered through the in-vitro gastrointestinal digestion phases (concentration loss: 11% for 3-DG, 24% for GO and MGO) and have an effect on the fermentative digestion process, reducing the total gut bacterial population up to 6 Log

Identifiants

DOI: 10.1016/j.foodchem.2020.128237 PMID: 33091666
pubmed: 33091666
pii: S0308-8146(20)32099-9
doi: 10.1016/j.foodchem.2020.128237
pii:
doi:

Substances chimiques

Aldehydes 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

128237

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Auteurs

Selina Brighina (S)

Dipartimento di Agricoltura, Alimentazione e Ambiente (Di3A), Università degli Studi di Catania, Via S.Sofia 100, 95123 Catania, Italy. Electronic address: selina.brighina@unict.it.

Carlos Poveda Turrado (C)

Department of Food and Nutritional Sciences, University of Reading (United Kingdom), PO Box 226, Whiteknights, Reading (UK), RG6 6AP, UK. Electronic address: g.povedaturrado@reading.ac.uk.

Cristina Restuccia (C)

Dipartimento di Agricoltura, Alimentazione e Ambiente (Di3A), Università degli Studi di Catania, Via S.Sofia 100, 95123 Catania, Italy. Electronic address: cristina.restuccia@unict.it.

Gemma Walton (G)

Department of Food and Nutritional Sciences, University of Reading (United Kingdom), PO Box 226, Whiteknights, Reading (UK), RG6 6AP, UK. Electronic address: g.e.walton@reading.ac.uk.

Biagio Fallico (B)

Dipartimento di Agricoltura, Alimentazione e Ambiente (Di3A), Università degli Studi di Catania, Via S.Sofia 100, 95123 Catania, Italy. Electronic address: biagio.fallico@unict.it.

Maria Jose Oruna-Concha (MJ)

Department of Food and Nutritional Sciences, University of Reading (United Kingdom), PO Box 226, Whiteknights, Reading (UK), RG6 6AP, UK. Electronic address: m.j.oruna-concha@reading.ac.uk.

Elena Arena (E)

Dipartimento di Agricoltura, Alimentazione e Ambiente (Di3A), Università degli Studi di Catania, Via S.Sofia 100, 95123 Catania, Italy. Electronic address: elena.arena@unict.it.

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Aldéhydes › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil buccodentaire et de l'appareil digestif › Phénomènes physiologiques de l'appareil digestif › Digestion › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Fermentation › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Tissus › Membranes › Muqueuse › Muqueuse intestinale › Detrimental effect on the gut microbiota of...
questionsmedicales.fr › Système digestif › Tube digestif › Tube digestif supérieur › Estomac › Detrimental effect on the gut microbiota of...