Advances in the development of entry inhibitors for sialic-acid-targeting viruses.
Journal
Drug discovery today
ISSN: 1878-5832
Titre abrégé: Drug Discov Today
Pays: England
ID NLM: 9604391
Informations de publication
Date de publication:
01 2021
01 2021
Historique:
received:
09
04
2020
revised:
13
07
2020
accepted:
13
10
2020
pubmed:
26
10
2020
medline:
18
12
2021
entrez:
25
10
2020
Statut:
ppublish
Résumé
Over the past decades, several antiviral drugs have been developed to treat a range of infections. Yet the number of treatable viral infections is still limited, and resistance to current drug regimens is an ever-growing problem. Therefore, additional strategies are needed to provide a rapid cure for infected individuals. An interesting target for antiviral drugs is the process of viral attachment and entry into the cell. Although most viruses use distinct host receptors for attachment to the target cell, some viruses share receptors, of which sialic acids are a common example. This review aims to give an update on entry inhibitors for a range of sialic-acid-targeting viruses and provides insight into the prospects for those with broad-spectrum potential.
Identifiants
pubmed: 33099021
pii: S1359-6446(20)30424-4
doi: 10.1016/j.drudis.2020.10.009
pmc: PMC7577316
pii:
doi:
Substances chimiques
Antiviral Agents
0
Receptors, Virus
0
N-Acetylneuraminic Acid
GZP2782OP0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
122-137Informations de copyright
Copyright © 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
Références
J Virol. 2015 Sep;89(17):8880-96
pubmed: 26085147
Clin Infect Dis. 2016 Sep 15;63(6):737-745
pubmed: 27318332
Antiviral Res. 2009 Feb;81(2):132-40
pubmed: 19028526
Eur J Med Chem. 2016 Mar 3;110:376-88
pubmed: 26866456
Nat Struct Mol Biol. 2019 Dec;26(12):1151-1157
pubmed: 31792450
J Infect Dis. 2010 Jul 15;202(2):234-41
pubmed: 20533871
J Am Soc Nephrol. 1999 May;10(5):1080-9
pubmed: 10232695
Vaccines (Basel). 2018 May 21;6(2):
pubmed: 29883414
Lancet. 2020 Feb 22;395(10224):565-574
pubmed: 32007145
PLoS One. 2010 Feb 08;5(2):e9106
pubmed: 20161706
J Med Chem. 2018 Jan 11;61(1):98-118
pubmed: 29220568
Annu Rev Nutr. 2009;29:177-222
pubmed: 19575597
J Clin Virol. 2010 Apr;47(4):306-12
pubmed: 20060360
Immunity. 2017 Apr 18;46(4):587-595
pubmed: 28423338
Transplantation. 2007 Aug 15;84(3):323-30
pubmed: 17700156
Antimicrob Agents Chemother. 2018 Oct 24;62(11):
pubmed: 30150460
Nano Lett. 2019 Mar 13;19(3):1875-1882
pubmed: 30719917
N Engl J Med. 2016 Mar 10;374(10):951-8
pubmed: 26862926
Angew Chem Int Ed Engl. 2012 Oct 15;51(42):10472-98
pubmed: 22952048
Front Immunol. 2019 Oct 22;10:2476
pubmed: 31749796
Virology. 1983 Jun;127(2):361-73
pubmed: 6868370
Eur J Med Chem. 2015 Mar 26;93:182-95
pubmed: 25681711
PLoS One. 2009 Nov 06;4(11):e7838
pubmed: 19893749
J Virol. 2007 Aug;81(15):8341-5
pubmed: 17522226
Philos Trans R Soc Lond B Biol Sci. 2012 Oct 19;367(1604):2864-71
pubmed: 22966141
Br J Exp Pathol. 1985 Oct;66(5):543-9
pubmed: 4063159
Biomaterials. 2017 Sep;138:22-34
pubmed: 28550754
J Virol. 1998 Sep;72(9):7367-73
pubmed: 9696833
J Infect Dis. 2002 Dec 1;186 Suppl 2:S180-6
pubmed: 12424695
mBio. 2018 Oct 16;9(5):
pubmed: 30327438
J Virol. 2015 Jul;89(14):7202-13
pubmed: 25926653
Emerg Microbes Infect. 2019;8(1):516-530
pubmed: 30938227
Virology. 2014 Sep;464-465:424-431
pubmed: 25146600
N Engl J Med. 2020 Feb 20;382(8):727-733
pubmed: 31978945
Nature. 1982 Mar 11;296(5853):115-21
pubmed: 6174870
Antimicrob Agents Chemother. 2006 Apr;50(4):1470-9
pubmed: 16569867
J Biol Chem. 2003 Nov 28;278(48):48245-50
pubmed: 14500706
Cell Rep. 2015 Jun 30;11(12):1966-78
pubmed: 26095364
Adv Sci (Weinh). 2020 Dec 14;8(3):2001012
pubmed: 33552848
Clin Microbiol Rev. 2016 Jul;29(3):695-747
pubmed: 27281742
J Infect Dis. 2010 Apr 1;201(7):1007-15
pubmed: 20170378
Antimicrob Agents Chemother. 2016 Mar 25;60(4):2118-31
pubmed: 26787699
Nat Commun. 2015 Nov 13;6:8865
pubmed: 26563423
Org Biomol Chem. 2015 Sep 21;13(35):9194-205
pubmed: 26177934
Adv Carbohydr Chem Biochem. 2019;76:65-111
pubmed: 30851744
Antimicrob Agents Chemother. 2017 Oct 24;61(11):
pubmed: 28807912
J Antimicrob Chemother. 2009 Feb;63(2):421-2
pubmed: 19022776
Cell. 2016 Jul 28;166(3):596-608
pubmed: 27453466
Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1399-404
pubmed: 26787879
Arch Virol. 2018 Feb;163(2):299-317
pubmed: 29058149
Nat Nanotechnol. 2020 May;15(5):373-379
pubmed: 32231271
Cell Host Microbe. 2018 Jun 13;23(6):809-818.e5
pubmed: 29779930
Am J Physiol Lung Cell Mol Physiol. 2002 Mar;282(3):L563-72
pubmed: 11839553
Clin Microbiol Rev. 2003 Apr;16(2):242-64
pubmed: 12692097
Front Microbiol. 2018 Aug 07;9:1826
pubmed: 30131793
Nat Nanotechnol. 2017 Jan;12(1):48-54
pubmed: 27775724
Nat Rev Microbiol. 2014 Nov;12(11):739-49
pubmed: 25263223
J Virol. 1994 Oct;68(10):6811-4
pubmed: 8084019
J Infect Dis. 2014 Aug 1;210(3):435-40
pubmed: 24569063
Nat Med. 2003 Nov;9(11):1408-12
pubmed: 14566335
Trends Microbiol. 2016 Dec;24(12):991-1001
pubmed: 27491885
Nat Rev Drug Discov. 2016 May;15(5):327-47
pubmed: 26868298
Angew Chem Int Ed Engl. 2011 Jul 11;50(29):6519-21
pubmed: 21648036
J Infect Dis. 2017 Aug 1;216(3):356-365
pubmed: 28633457
Bioorg Med Chem. 2020 Jan 1;28(1):115130
pubmed: 31753804
Angew Chem Int Ed Engl. 2020 Jul 20;59(30):12417-12422
pubmed: 32441859
Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8508-E8517
pubmed: 28923942
mBio. 2020 Feb 11;11(1):
pubmed: 32047132
MMWR Morb Mortal Wkly Rep. 2016 Jan 29;65(3):59-62
pubmed: 26820244
Virology. 2015 Jan 1;474:110-6
pubmed: 25463609
Nat Microbiol. 2020 Jan;5(1):4-5
pubmed: 31857727
Virology. 2002 Oct 10;302(1):33-43
pubmed: 12429514
Sci Adv. 2019 Sep 04;5(9):eaax3567
pubmed: 31517055
Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):10890-5
pubmed: 26283346
Am J Physiol. 1997 Dec;273(6):L1156-66
pubmed: 9435570
Nat Struct Mol Biol. 2019 Jun;26(6):481-489
pubmed: 31160783
Emerg Microbes Infect. 2019;8(1):426-437
pubmed: 30898036
J Infect Dis. 2017 Dec 16;216(suppl_10):S935-S944
pubmed: 29267925
Biochem Soc Trans. 1995 Nov;23(4):836-9
pubmed: 8654849
Adv Nutr. 2012 May 01;3(3):465S-72S
pubmed: 22585926
Science. 2008 Feb 22;319(5866):1096-100
pubmed: 18202256
Respir Med. 1993 Aug;87(6):421-6
pubmed: 8210612
Antimicrob Agents Chemother. 2009 Sep;53(9):3942-51
pubmed: 19564364
Chembiochem. 2005 Feb;6(2):358-64
pubmed: 15678425
EBioMedicine. 2016 Feb 26;5:147-55
pubmed: 27077121
Rev Med Virol. 2003 Mar-Apr;13(2):85-97
pubmed: 12627392
J Infect Dis. 2009 Dec 15;200(12):1870-3
pubmed: 19911992
PLoS One. 2016 Jul 14;11(7):e0159074
pubmed: 27415624
Nature. 2013 Mar 14;495(7440):251-4
pubmed: 23486063
Lancet Neurol. 2010 Apr;9(4):425-37
pubmed: 20298966
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Jun;26(3):289-93
pubmed: 15266832
Ter Arkh. 2005;77(8):84-8
pubmed: 16206613
J Neurosci Res. 1996 Jul 15;45(2):143-52
pubmed: 8843031
Sci Rep. 2018 Jun 12;8(1):8989
pubmed: 29895962
Science. 2019 Mar 8;363(6431):
pubmed: 30846569
Viruses. 2018 Apr 10;10(4):
pubmed: 29642580
Curr Allergy Asthma Rep. 2017 Mar;17(3):16
pubmed: 28283855
Small. 2010 Dec 20;6(24):2900-6
pubmed: 21104827
PLoS One. 2015 Sep 18;10(9):e0138426
pubmed: 26382764
Clinics (Sao Paulo). 2018 Oct 11;73(suppl 1):e558s
pubmed: 30328951
Front Microbiol. 2018 Nov 01;9:2660
pubmed: 30443246
J Antimicrob Chemother. 2015 Oct;70(10):2797-809
pubmed: 26169554
Proc Natl Acad Sci U S A. 2018 Apr 17;115(16):4240-4245
pubmed: 29610325
Curr Biol. 2010 Nov 23;20(22):2003-9
pubmed: 20970336
J Virol. 1998 Jan;72(1):415-9
pubmed: 9420240
Annu Rev Pathol. 2008;3:499-522
pubmed: 18039138
Antiviral Res. 2002 Jul;55(1):201-5
pubmed: 12076764
Lab Invest. 1996 May;74(5):907-20
pubmed: 8642786
J Infect Dis. 1995 Feb;171(2):335-41
pubmed: 7844369
J Virol. 2014 Mar;88(5):2374-84
pubmed: 24371050
Proc Natl Acad Sci U S A. 1988 Jun;85(12):4526-9
pubmed: 3380803
Eur J Med Chem. 2020 May 15;194:112223
pubmed: 32220685
Clin Infect Dis. 2020 Aug 14;71(4):1092-1094
pubmed: 31538179
Chem Rev. 2002 Feb;102(2):439-69
pubmed: 11841250
Bone Marrow Transplant. 2001 Mar;27(6):621-6
pubmed: 11319592
Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10696-701
pubmed: 21670291
Cell Host Microbe. 2010 Oct 21;8(4):309-19
pubmed: 20951965
Biochimie. 1998 Jan;80(1):49-57
pubmed: 9587662
J Virol. 2005 Nov;79(22):14442-5
pubmed: 16254379
J Virol. 2013 Aug;87(16):9379-83
pubmed: 23785207
Proc Natl Acad Sci U S A. 2019 Feb 12;116(7):2681-2690
pubmed: 30679277
Antiviral Res. 1996 Jul;31(3):165-72
pubmed: 8811201
J Virol. 2008 Mar;82(5):2560-4
pubmed: 18094176
N Engl J Med. 2001 Jun 21;344(25):1917-28
pubmed: 11419430
Nat Mater. 2018 Feb;17(2):195-203
pubmed: 29251725
Angew Chem Int Ed Engl. 2020 Sep 1;59(36):15532-15536
pubmed: 32421225
J Virol. 2019 Mar 5;93(6):
pubmed: 30626687
Sci Adv. 2019 Apr 10;5(4):eaav4580
pubmed: 30989115
Front Microbiol. 2018 Nov 13;9:2677
pubmed: 30483226
Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4264-E4273
pubmed: 29674446
Sci Rep. 2020 Jan 21;10(1):768
pubmed: 31964943
mBio. 2019 Feb 19;10(1):
pubmed: 30782664
Cell Mol Life Sci. 2006 Apr;63(7-8):865-76
pubmed: 16501889
Antiviral Res. 2020 May;177:104782
pubmed: 32222293
J Med Virol. 2019 Apr;91(4):588-597
pubmed: 30431664
Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):206-214
pubmed: 28003465
Viruses. 2015 Dec 25;8(1):
pubmed: 26712783
Proc R Soc Lond B Biol Sci. 1982 Mar 22;214(1197):471-80
pubmed: 6127692
J Virol. 2019 Aug 13;93(17):
pubmed: 31167918
Eur J Microbiol Immunol (Bp). 2014 Mar;4(1):26-33
pubmed: 24678403
Sci Transl Med. 2019 Jul 24;11(502):
pubmed: 31341062
Antiviral Res. 2007 Feb;73(2):92-100
pubmed: 17014916
Cell Host Microbe. 2013 Jul 17;14(1):93-103
pubmed: 23870317
PLoS Pathog. 2012;8(7):e1002738
pubmed: 22910713
Expert Rev Respir Med. 2011 Aug;5(4):515-26
pubmed: 21859271
Nat Microbiol. 2020 Jan;5(1):27-33
pubmed: 31768027
J Med Chem. 2020 Mar 26;63(6):3120-3130
pubmed: 32069052
Antiviral Res. 2015 Nov;123:114-9
pubmed: 26391974
Clin Pharmacokinet. 2018 Mar;57(3):367-377
pubmed: 28639229
Trends Mol Med. 2008 Aug;14(8):351-60
pubmed: 18606570
Viruses. 2020 Feb 18;12(2):
pubmed: 32085430
J Antimicrob Chemother. 2008 Aug;62(2):426-8; author reply 428-9
pubmed: 18434340
Biomedicines. 2018 Mar 07;6(1):
pubmed: 29518985
Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2344-50
pubmed: 26092189
Am J Phys Anthropol. 2001;Suppl 33:54-69
pubmed: 11786991
Chembiochem. 2011 Apr 11;12(6):887-95
pubmed: 21384484
Viruses. 2019 May 05;11(5):
pubmed: 31060278
Nature. 2007 Apr 26;446(7139):1023-9
pubmed: 17460663
Antimicrob Agents Chemother. 2004 May;48(5):1495-502
pubmed: 15105096
J Virol. 1998 Jun;72(6):4643-9
pubmed: 9573227
Nat Med. 2011 Jan;17(1):105-9
pubmed: 21151139
J Virol. 2000 Aug;74(16):7691-3
pubmed: 10906228
Annu Rev Biochem. 2000;69:531-69
pubmed: 10966468
J Infect Dis. 2004 Aug 1;190(3):519-26
pubmed: 15243927
J Infect Dis. 2012 Dec 15;206(12):1844-51
pubmed: 23045618
J Antimicrob Chemother. 2008 Aug;62(2):219-23
pubmed: 18238888
J Pept Sci. 2015 Mar;21(3):236-42
pubmed: 25522925
Lancet Infect Dis. 2018 Aug;18(8):e239-e247
pubmed: 29482893
Microbiol Immunol. 2000;44(6):423-30
pubmed: 10941924
Beilstein J Org Chem. 2015 May 15;11:804-16
pubmed: 26124882
J Biol Chem. 2013 Mar 22;288(12):8061-8073
pubmed: 23362274
J Infect Dis. 2020 Jan 14;221(3):346-355
pubmed: 31309975
Front Immunol. 2018 Jul 20;9:1581
pubmed: 30079062
Mol Pharm. 2020 Jul 6;17(7):2546-2554
pubmed: 32426985
Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6401-6
pubmed: 24733924
J Virol. 1999 Jul;73(7):5826-32
pubmed: 10364334
Curr Med Chem. 2008;15(10):997-1005
pubmed: 18393857
PLoS One. 2009 Nov 06;4(11):e7788
pubmed: 19893747
Angew Chem Int Ed Engl. 1998 Nov 2;37(20):2754-2794
pubmed: 29711117
J Gen Virol. 2014 Feb;95(Pt 2):263-277
pubmed: 24225499
Lancet Infect Dis. 2016 May;16(5):e64-e75
pubmed: 26929196
J Prev Med Hyg. 2014 Sep;55(3):69-85
pubmed: 25902573
J Infect. 2014 Jan;68 Suppl 1:S2-8
pubmed: 24119828
J Infect Dis. 2020 Jan 14;221(3):367-371
pubmed: 31541547
Biochem Pharmacol. 2017 Nov 15;144:35-51
pubmed: 28774731
Antimicrob Agents Chemother. 2015 Dec;59(12):7779-81
pubmed: 26149998
Front Immunol. 2018 Sep 10;9:1946
pubmed: 30250466
Rev Med Virol. 2009 May;19(3):165-78
pubmed: 19367611
J Infect Dis. 2019 Apr 8;219(Suppl_1):S62-S67
pubmed: 30715353
J Infect Dis. 2005 Jul 15;192(2):249-57
pubmed: 15962219
Front Microbiol. 2018 Nov 06;9:2643
pubmed: 30459739
Antivir Ther. 2009;14(7):891-8
pubmed: 19918093
Influenza Other Respir Viruses. 2008 Sep;2(5):147-54
pubmed: 19453419
EBioMedicine. 2019 Feb;40:574-582
pubmed: 30638863
Virology. 1966 Dec;30(4):731-7
pubmed: 5951649
Emerg Infect Dis. 2017 Jan;23(1):140-143
pubmed: 27660916
Cell Host Microbe. 2016 Nov 9;20(5):631-641
pubmed: 27923705
Antiviral Res. 2005 Dec;68(3):116-23
pubmed: 16214231
Virology. 1997 Jun 9;232(2):345-50
pubmed: 9191848
Emerg Infect Dis. 2016 Jul;22(7):1185-92
pubmed: 27070380
Biol Blood Marrow Transplant. 2016 May;22(5):965-70
pubmed: 26904972
Bioorg Med Chem. 2017 Aug 15;25(16):4384-4396
pubmed: 28651913
J Virol. 2000 Jan;74(1):42-8
pubmed: 10590089
Vaccines (Basel). 2019 Nov 01;7(4):
pubmed: 31683930