A bifunctional DNA probe for sensing pH and microRNA using a nanopore.

Biosensing Techniques DNA Probes / genetics Hydrogen-Ion Concentration MicroRNAs / genetics Nanopores

Journal

The Analyst
ISSN: 1364-5528
Titre abrégé: Analyst
Pays: England
ID NLM: 0372652

Informations de publication

Date de publication:
26 Oct 2020
Historique:
entrez: 26 10 2020
pubmed: 27 10 2020
medline: 15 5 2021
Statut: ppublish

Résumé

We have developed a bifunctional probe based on triplex molecular beacons for the measurement of environmental pH and quantification of microRNA-10b using a nanopore. The probe responds sharply to solution pH changes in the range of 6.0-7.5. The limit of detection for microRNA-10b is as low as 5.0 pM.

Identifiants

DOI: 10.1039/d0an01208d PMID: 33103667
pubmed: 33103667
doi: 10.1039/d0an01208d
doi:

Substances chimiques

DNA Probes 0
MicroRNAs 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

7025-7029

Commentaires et corrections

Type : ErratumIn

Auteurs

Yun Zhang (Y)

Beijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China. haichenwu@iccas.ac.cn.

Peng Song (P)

Bingyuan Guo (B)

Wenying Hao (W)

Lei Liu (L)

Hai-Chen Wu (HC)

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de sonde moléculaire › Techniques de biocapteur › A bifunctional DNA probe for sensing pH and...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Sondes moléculaires › Sondes d'acide nucléique › Sondes d'ADN › A bifunctional DNA probe for sensing pH and...
questionsmedicales.fr › Phénomènes chimiques › Concentration en ions d'hydrogène › A bifunctional DNA probe for sensing pH and...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › A bifunctional DNA probe for sensing pH and...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanopores › A bifunctional DNA probe for sensing pH and...