Unresectable Chondrosarcomas Treated With Carbon Ion Radiotherapy: Relationship Between Dose-averaged Linear Energy Transfer and Local Recurrence.


Journal

Anticancer research
ISSN: 1791-7530
Titre abrégé: Anticancer Res
Pays: Greece
ID NLM: 8102988

Informations de publication

Date de publication:
Nov 2020
Historique:
received: 28 09 2020
revised: 05 10 2020
accepted: 06 10 2020
entrez: 28 10 2020
pubmed: 29 10 2020
medline: 4 11 2020
Statut: ppublish

Résumé

The local control rate of chondrosarcomas treated with carbon-ion radiotherapy (CIRT) worsens as tumour size increases, possibly because of the intra-tumoural linear energy transfer (LET) distribution. This study aimed to evaluate the relationship between local recurrence and intra-tumoural LET distribution in chondrosarcomas treated with CIRT. Thirty patients treated with CIRT for grade 2 chondrosarcoma were included. Dose-averaged LET (LET The mean LET LET

Sections du résumé

BACKGROUND/AIM OBJECTIVE
The local control rate of chondrosarcomas treated with carbon-ion radiotherapy (CIRT) worsens as tumour size increases, possibly because of the intra-tumoural linear energy transfer (LET) distribution. This study aimed to evaluate the relationship between local recurrence and intra-tumoural LET distribution in chondrosarcomas treated with CIRT.
PATIENTS AND METHODS METHODS
Thirty patients treated with CIRT for grade 2 chondrosarcoma were included. Dose-averaged LET (LET
RESULTS RESULTS
The mean LET
CONCLUSION CONCLUSIONS
LET

Identifiants

pubmed: 33109581
pii: 40/11/6429
doi: 10.21873/anticanres.14664
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

6429-6435

Informations de copyright

Copyright© 2020, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

Auteurs

Shinnosuke Matsumoto (S)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan matsumoto.shinnosuke@qst.go.jp.

Sung Hyun Lee (SH)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Reiko Imai (R)

QST Hospital, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Taku Inaniwa (T)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Naruhiro Matsufuji (N)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Mai Fukahori (M)

QST Hospital, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Ryosuke Kohno (R)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Shunsuke Yonai (S)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Noriyuki Okonogi (N)

QST Hospital, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Shigeru Yamada (S)

QST Hospital, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

Nobuyuki Kanematsu (N)

Department of Accelerator and Medical Physics, National Institute of Radiological Sciences, Quantum Medical Science Directorate, National Institutes for Quantum and Radiological Science and Technology, Chiba, Japan.

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Classifications MeSH