Impaired mitochondrial medium-chain fatty acid oxidation drives periportal macrovesicular steatosis in sirtuin-5 knockout mice.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
27 10 2020
Historique:
received: 02 04 2020
accepted: 08 10 2020
entrez: 28 10 2020
pubmed: 29 10 2020
medline: 11 3 2021
Statut: epublish

Résumé

Medium-chain triglycerides (MCT), containing C

Identifiants

pubmed: 33110171
doi: 10.1038/s41598-020-75615-3
pii: 10.1038/s41598-020-75615-3
pmc: PMC7591893
doi:

Substances chimiques

Dietary Fats 0
Fatty Acids 0
SIRT5 protein, mouse 0
Triglycerides 0
Acyl-CoA Dehydrogenase, Long-Chain EC 1.3.8.8
Sirtuins EC 3.5.1.-
Coconut Oil Q9L0O73W7L

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

18367

Subventions

Organisme : NIDDK NIH HHS
ID : R01 DK062277
Pays : United States
Organisme : NIDDK NIH HHS
ID : 090242
Pays : United States
Organisme : NIDDK NIH HHS
ID : P30 DK120531
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK100287
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK090242
Pays : United States

Références

Biochimie. 2014 Mar;98:4-15
pubmed: 24075875
J Biol Chem. 1991 Feb 15;266(5):2924-9
pubmed: 1993666
J Clin Invest. 1996 Nov 15;98(10):2244-50
pubmed: 8941640
Eur J Biochem. 1996 Dec 1;242(2):186-90
pubmed: 8973631
Hepatology. 2019 Feb;69(2):742-759
pubmed: 30215850
Epilepsia Open. 2019 Feb 22;4(1):153-163
pubmed: 30868125
J Biol Chem. 2012 Jan 2;287(1):210-21
pubmed: 22045812
Pediatr Res. 1997 Jul;42(1):108-13
pubmed: 9212045
Redox Biol. 2019 Sep;26:101253
pubmed: 31234015
J Biol Chem. 2004 May 7;279(19):19574-9
pubmed: 14982940
Mol Genet Metab. 2010 Jun;100(2):163-7
pubmed: 20363655
J Biol Chem. 1996 Jul 12;271(28):16748-52
pubmed: 8663269
Cell Rep. 2013 Oct 17;5(1):248-58
pubmed: 24075987
Cochrane Database Syst Rev. 2019 Jun 04;6:CD013171
pubmed: 31158920
Biochim Biophys Acta. 1999 Aug 5;1428(2-3):455-62
pubmed: 10434065
J Inherit Metab Dis. 2017 Nov;40(6):831-843
pubmed: 28871440
J Am Soc Nephrol. 2019 Dec;30(12):2384-2398
pubmed: 31575700
Cell Metab. 2014 Apr 1;19(4):605-17
pubmed: 24703693
J Inherit Metab Dis. 2010 Oct;33(5):479-94
pubmed: 20490924
Mol Genet Metab. 2010 Sep;101(1):40-7
pubmed: 20580297
Biochim Biophys Acta. 1981 Dec 23;666(3):394-404
pubmed: 6798996
J Lipid Res. 2007 Dec;48(12):2736-50
pubmed: 17762044
EMBO Rep. 2018 May;19(5):
pubmed: 29491006
J Histochem Cytochem. 1999 Oct;47(10):1219-32
pubmed: 10490450
Biochim Biophys Acta. 1991 Jan 28;1081(2):167-73
pubmed: 1998734
Biochim Biophys Acta. 1998 Jul 31;1393(1):35-40
pubmed: 9714723
Anal Chem. 1975 Jul;47(8):1313-21
pubmed: 1147254
Neurobiol Dis. 2011 Feb;41(2):279-90
pubmed: 20887790
Clin Gastroenterol Hepatol. 2018 Mar;16(3):438-446.e1
pubmed: 28286193
Front Nutr. 2019 Apr 16;6:46
pubmed: 31058159
J Biol Chem. 2013 Nov 22;288(47):33837-47
pubmed: 24121500
Plant Foods Hum Nutr. 2017 Dec;72(4):418-424
pubmed: 29079969
Biochem J. 1995 Nov 1;311 ( Pt 3):853-60
pubmed: 7487941
J Sci Food Agric. 2018 Mar;98(5):1757-1764
pubmed: 28862329
Hum Mutat. 2007 Sep;28(9):904-12
pubmed: 17458872
J Biol Chem. 2017 Jun 16;292(24):10239-10249
pubmed: 28458255
Annu Rev Nutr. 2014;34:1-30
pubmed: 24819326
Physiol Rev. 1983 Oct;63(4):1420-80
pubmed: 6361812
J Inherit Metab Dis. 2020 Jan;43(1):71-89
pubmed: 30864148
Mol Genet Metab. 2020 May 1;:
pubmed: 32389575
PLoS One. 2015 Mar 26;10(3):e0122297
pubmed: 25811481
Biochem Biophys Res Commun. 2007 Aug 24;360(2):314-9
pubmed: 17603022
Curr Nutr Rep. 2018 Sep;7(3):107-115
pubmed: 29974400
Clin Chem. 1978 Oct;24(10):1674-9
pubmed: 699272
Biochim Biophys Acta. 2009 Aug;1791(8):806-15
pubmed: 19465148
Mol Cell. 2015 Jul 16;59(2):321-32
pubmed: 26073543
Br J Nutr. 1999 Oct;82(4):299-308
pubmed: 10655979
Biochem J. 2005 Jul 15;389(Pt 2):397-401
pubmed: 15773815
Ghana Med J. 2016 Sep;50(3):189-196
pubmed: 27752194
Cell Metab. 2013 Dec 3;18(6):920-33
pubmed: 24315375
Sci Rep. 2016 Apr 07;6:24156
pubmed: 27052737
Methods Mol Biol. 2018;1782:137-155
pubmed: 29850998
Nat Commun. 2018 Jul 27;9(1):2940
pubmed: 30054481
Mol Metab. 2014 Mar 06;3(4):354-71
pubmed: 24944896

Auteurs

Eric S Goetzman (ES)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. eric.goetzman@chp.edu.
Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. eric.goetzman@chp.edu.

Sivakama S Bharathi (SS)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Yuxun Zhang (Y)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Xue-Jun Zhao (XJ)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Steven F Dobrowolski (SF)

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Kevin Peasley (K)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Sunder Sims-Lucas (S)

Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Satdarshan P Monga (SP)

Division of Experimental Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Pittsburgh Liver Research Center, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

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Classifications MeSH