Development of a Rapid, Antimicrobial Susceptibility Test for

Escherichia coli (E. coli) antibiotic susceptibility testing (AST) electrochemistry growth-profiles real-time monitoring screen-printed electrodes (SPEs) streptomycin

Journal

Biosensors
ISSN: 2079-6374
Titre abrégé: Biosensors (Basel)
Pays: Switzerland
ID NLM: 101609191

Informations de publication

Date de publication:
23 Oct 2020
Historique:
received: 29 09 2020
revised: 20 10 2020
accepted: 22 10 2020
entrez: 29 10 2020
pubmed: 30 10 2020
medline: 23 4 2021
Statut: epublish

Résumé

Antibiotic resistance has been cited by the World Health Organisation (WHO) as one of the greatest threats to public health. Mitigating the spread of antibiotic resistance requires a multipronged approach with possible interventions including faster diagnostic testing and enhanced antibiotic stewardship. This study employs a low-cost diagnostic sensor test to rapidly pinpoint the correct antibiotic for treatment of infection. The sensor comprises a screen-printed gold electrode, modified with an antibiotic-seeded hydrogel to monitor bacterial growth. Electrochemical growth profiles of the common microorganism,

Identifiants

pubmed: 33114106
pii: bios10110153
doi: 10.3390/bios10110153
pmc: PMC7690799
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Medical Research Council
ID : MC_PC_17178
Pays : United Kingdom
Organisme : Medical Research Council
ID : R180246-103
Pays : United Kingdom

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Auteurs

Stuart Hannah (S)

Department of Biomedical Engineering, University of Strathclyde, 40 George Street, Glasgow G1 1QE, UK.

Alexandra Dobrea (A)

Department of Biomedical Engineering, University of Strathclyde, 40 George Street, Glasgow G1 1QE, UK.

Perrine Lasserre (P)

Department of Biomedical Engineering, University of Strathclyde, 40 George Street, Glasgow G1 1QE, UK.

Ewen O Blair (EO)

Department of Biomedical Engineering, University of Strathclyde, 40 George Street, Glasgow G1 1QE, UK.

David Alcorn (D)

Division of Anaesthesia, Royal Alexandra Hospital, Corsebar Road, Paisley PA2 9PN, UK.

Paul A Hoskisson (PA)

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow G4 0RE, UK.

Damion K Corrigan (DK)

Department of Biomedical Engineering, University of Strathclyde, 40 George Street, Glasgow G1 1QE, UK.

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Classifications MeSH